Effects of remote ischemic postconditioning on HIF-1α and other markers in on-pump cardiac surgery

The Signaling Mechanism of Remote Postconditioning of the Heart: Prospects of the Use of Remote Postconditioning for the Treatment of Acute Myocardial Infarction

“…It is possible that for this reason, RPost had no effect on post-infarction remodeling of the heart. A study included patients (n = 70) undergoing on-pump cardiac surgery [ 62 ]. RPost was performed by 3 cycles of ischemia (5 min) and reperfusion (5 min) of the arm.…”

“…RPost was performed by 3 cycles of ischemia (5 min) and reperfusion (5 min) of the arm. It was found that RPost reduced the plasma troponin T and CK-MB levels [ 62 ]. These data demonstrated that RPost can mitigate reperfusion cardiac injury.…”

“…There is evidence that RPost can increase cardiac tolerance to reperfusion [ 55 , 57 , 62 ]. There are data that indicate that RPost does not affect cardiac tolerance to reperfusion [ 15 , 54 , 56 , 58 , 59 , 60 ].…”

“…In summary, the data on the efficacy of RPost in clinical practice are inconsistent (Table 3). There is evidence that RPost can increase cardiac tolerance to reperfusion [55,57,62]. There are data that indicate that RPost does not affect cardiac tolerance to reperfusion [15,54,56,[58][59][60].…”