Effects of rutin supplementation on growth performance, slaughter performance, serum parameters, and meat quality of Nubian goats

Jinshun, Zhan; Gu, Zhiyong; Wang, Haibo; Liu, Yuhang; Wang, Liyuan; Huang, Liewu; Huo, Jun-Hong; Wu, Yanping

doi:10.1111/asj.13819

Cited by 6 publications

(3 citation statements)

References 53 publications

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“…Slaughter performance, including carcass weight and dressing percentage, directly manifests the growth performance and economic value of animals [ 5 , 15 ]. Differences among treatments in SBW, EBW, HCW, net meat percentage, the ratio of meat to bone, and visceral fat percentage were observed at both stages in this study.…”

Section: Discussionmentioning

confidence: 99%

“…A balanced nutritional feed has been found to promote the growth and development of dairy goats, improving their milk production performance during lactation [ 4 ]. Adequate protein intake also enhances their growth rate and muscle development [ 5 , 6 ]. Research on organ development in dairy goats has primarily focused on the mammary gland and digestive system [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Effect of Feeding Level on Growth and Slaughter Performance, and Allometric Growth of Tissues and Organs in Female Growing Saanen Dairy Goats

Huang,

Jiao,

et al. 2024

Animals

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This study aimed to investigate the effect of feeding level on the growth and slaughter performance, and allometric growth of tissues and organs in female growing dairy goats. The trial included 10–20 and 20–30 kg weight stages with 48 female goat kids. The 24 goat kids in each stage were divided into 8 blocks based on weight, with 3 kids per block. Then, three kids from each block were randomly assigned to one of the three treatments, namely ad libitum (AL100), 70% of ad libitum (AL70), or 40% of ad libitum (AL40). The slaughter trial was conducted when the AL100 kids reached the target weight of 20 or 30 kg. The results showed that the ADG and feed conversion rate showed a linear decline as the feed level decreased (p < 0.05). Compared with the AL70 and AL100 groups, the AL40 group exhibited lower shrunk body weight, empty body weight, hot carcass weight, net meat rate, carcass meat rate, and visceral fat weight (p < 0.05) in both stages. Moreover, the AL40 group showed lower weights for skin and mohair, blood, rumen, small intestine, large intestine, mammary gland, and uterus than the AL70 and AL100 groups (p < 0.05) in both stages. However, feeding level did not affect organ indices in the two stages (p > 0.05). The bone, skin and mohair were isometric (b ≈ 1), but the muscle, visceral fat, and most internal organs were positive (b > 1) in both stages. In conclusion, feeding level affects the growth and development of dairy goats, which vary depending on the body weight stage and specific tissues and organs.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of Feeding Level on Growth and Slaughter Performance, and Allometric Growth of Tissues and Organs in Female Growing Saanen Dairy Goats

Huang,

Jiao,

et al. 2024

Animals

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“…Rutin, or rutoside, quercetin-3- O -rutinoside, or vitamin P, is a natural flavonoid glycoside that is a secondary metabolite in plants, which has antioxidant, anti-hypertension, anti-diabetes, anti-inflammation, and cardioprotective functions. Previously, we reported that rutin promoted the growth performance of sheep by enhancing antioxidant capacity and rumen fermentation and regulating hormone secretion, and improved meat quality of goats [ 4 – 6 ]. These studies indicate that rutin might be used in ruminant production as a feed additive.…”

Section: Introductionmentioning

confidence: 99%

Rutin alleviated lipopolysaccharide-induced damage in goat rumen epithelial cells

Zhan,

Gu,

Wang

et al. 2024

Anim Biosci

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Objective: Rutin, also called vitamin P, is a flavonoids from plants. Previous studies have indicated that rutin can alleviate the injury of tissues and cells by inhibiting oxidative stress and ameliorating inflammation. There is no report on the protective effects of rutin on goat rumen epithelial cells (GRECs) at present. Hence, we investigated whether rutin can alleviate lipopolysaccharide (LPS)-induced damage in GRECs.Methods: GRECs were cultured in basal medium or basal medium containing 1 μg/mL LPS, or 1 μg/mL LPS and 20 μg/mL rutin. Six replicates were performed for each group. After 3-h culture, the GRECs were harvested to detect the relevant parameters.Results: Rutin significantly enhanced the cell activity (p<0.05) and transepithelial electrical resistance (TEER) (p<0.01) and significantly reduced the apoptosis rate (p<0.05) of LPSinduced GRECs. Rutin significantly increased superoxide dismutase, glutathione peroxidase, and catalase activity (p<0.01) and significantly decreased lactate dehydrogenase activity and reactive oxygen species and malondialdehyde (MDA) levels in LPS-induced GRECs (p<0.01). The mRNA and protein levels of interleukin 6 (IL-6), IL-1β, and C-X-C motif chemokine ligand 8 (CXCL8) and the mRNA level of tumor necrosis factor-α (TNF-α) and chemokine C-C motif ligand 5 (CCL5) were significantly increased in LPS-induced GRECs (p<0.05 or p<0.01), while rutin supplementation significantly decreased the mRNA and protein levels of IL-6, TNF-α, and CXCL8 in LPS-induced GRECs (p<0.05 or p<0.01). The mRNA level of toll-like receptor 2 (TLR2), and the mRNA and protein levels of TLR4 and nuclear factor κB (NF-κB) was significantly improved in LPS-induced GRECs (p<0.05 or p<0.01), whereas rutin supplementation could significantly reduce the mRNA and protein levels of TLR4 (p<0.05 or p<0.01). In addition, rutin had a tendency of decreasing the protein levels of CXCL6, NF-κB, and inhibitor of nuclear factor kappa-B alpha (0.05< p<0.10). Rutin could significantly decreased interferon regulatory factor 3 mRNA expression in LPS-induced GRECs (p<0.05), whereas interferon induced protein with tetratricopeptide repeats 3 (IFIT3) and toll-interacting protein (TOLLIP) mRNA expression was not significantly different between the groups. LPS reduced the tight junction protein zonula occludin 1 (ZO-1) level in GRECs whereas rutin enhanced it. Rutin significantly improved tight junction protein Claudin-1 mRNA expression in LPS-induced GRECs (p<0.01), but could not affect tight junction protein Occludin mRNA expression.Conclusion: Rutin alleviated LPS-induced barrier damage in GRECs by improving oxidation resistance and anti-inflammatory activity, which may be related to TLR/NF-κB signaling pathway inhibition.

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Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock

Zhang,

Yang,

et al. 2024

Animal Nutrition

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Effects of rutin supplementation on growth performance, slaughter performance, serum parameters, and meat quality of Nubian goats

Cited by 6 publications

References 53 publications

Effect of Feeding Level on Growth and Slaughter Performance, and Allometric Growth of Tissues and Organs in Female Growing Saanen Dairy Goats

Effect of Feeding Level on Growth and Slaughter Performance, and Allometric Growth of Tissues and Organs in Female Growing Saanen Dairy Goats

Rutin alleviated lipopolysaccharide-induced damage in goat rumen epithelial cells

Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock

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