Effects of Sample Storage Conditions on Glycated Hemoglobin Measurement: Evaluation of Five Different High Performance Liquid Chromatography Methods

Little, Randie R.; Rohlfing, Curt L.; Tennill, Alethea L.; Connolly, Shawn; Hanson, Steve

doi:10.1089/dia.2006.0055

Cited by 57 publications

(55 citation statements)

References 12 publications

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“…Blood tubes should contain the anticoagulant specified by the manufacturer of the Hb A 1c assay method (EDTA can be used unless the manufacturer specifies otherwise). Sample stability is assay method specific (239,240 ). In general, whole-blood samples are stable for up to 1 week at 4°C (240 ).…”

Section: Iron Deficiency Anemia Increases Test Results (232 )mentioning

confidence: 99%

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

et al. 2011

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BACKGROUND Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. Draft guidelines were posted on the Internet and presented at the 2007 Arnold O. Beckman Conference. The document was modified in response to oral and written comments, and a revised draft was posted in 2010 and again modified in response to written comments. The National Academy of Clinical Biochemistry and the Evidence Based Laboratory Medicine Committee of the AACC jointly reviewed the guidelines, which were accepted after revisions by the Professional Practice Committee and subsequently approved by the Executive Committee of the American Diabetes Association. CONTENT In addition to long-standing criteria based on measurement of plasma glucose, diabetes can be diagnosed by demonstrating increased blood hemoglobin A1c (Hb A1c) concentrations. Monitoring of glycemic control is performed by self-monitoring of plasma or blood glucose with meters and by laboratory analysis of Hb A1c. The potential roles of noninvasive glucose monitoring, genetic testing, and measurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. SUMMARY The guidelines provide specific recommendations that are based on published data or derived from expert consensus. Several analytes have minimal clinical value at present, and their measurement is not recommended.

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Section: Iron Deficiency Anemia Increases Test Results (232 )mentioning

confidence: 99%

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

et al. 2011

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“…1 Prevalence of diabetesspecific retinopathy (moderate or more severe retinopathy) by vigintiles of the distribution of FPG, 2hPG and HbA 1c from the DETECT-2 analysis (adapted with permission from [57]). Indicative of chronic glycaemia [12] Results can be misleading in certain physiological and disease states [73] More convenient, as patient not required to fast and only one blood sample taken Not a direct measure of glycaemia Validated as a risk marker for complications and mortality [15][16][17][18]98] May vary with age and between different ethnic groups [65] Less intra-individual variability [99,100] More expensive, being unaffordable in many low and middle-income country settings [4] Greater pre-analytical stability [34,101] comes more widely used the epidemiological landscape of type 2 diabetes will be altered. It remains to be determined whether or not these supposed ethnic differences in HbA 1c are clinically consequential.…”

Section: Hba 1c For Diagnosismentioning

confidence: 99%

Current controversies in the use of haemoglobin A_1c

Hare

Shaw

Zimmet

2012

Journal of Internal Medicine

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Abstract. Hare MJL, Shaw JE, Zimmet PZ (Baker IDI Heart and Diabetes Institute, Melbourne, Vic.; and Monash University, Melbourne, Vic.; Australia). Current controversies in the use of haemoglobin A 1c (Review). J Intern Med 2012;271: 227-236.Haemoglobin A 1c (HbA 1c ) has recently been adopted by the World Health Organization into its recommended criteria for diabetes diagnosis. Much debate continues regarding the relative benefits and potential disadvantages surrounding the use of HbA 1c for this purpose. There is a lack of consensus as to whether this alteration to the definition of diabetes is a step forward or whether it could add further confusion and ambiguity to the debate on the method and criteria for the diagnosis of this globally important disease. This review provides a comprehensive overview of the current issues surrounding how HbA 1c is measured and reported; and of the evidence for and against its use in diagnosis.

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“…Кроме того, уровень HbA 1c относительно стабилен в образце крови, взятом для анализа [12,13]. Вариабель-ность HbA 1c при повторном заборе составляет менее 2%, а для ГПН -12-15% [14,15].…”

Section: Discussionunclassified

Optimizing screening procedures for early detection of glycemic disorders

Мисникова¹,

Dreval²,

Kovaleva³

et al. 2014

Diabetes mellitus

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Effects of Sample Storage Conditions on Glycated Hemoglobin Measurement: Evaluation of Five Different High Performance Liquid Chromatography Methods

Abstract: All methods either met or exceeded manufacturers' claims for stability. The CLC 385/330, Tosoh G7, and Bio-Rad Variant II high performance liquid chromatography methods showed better stability than the Tosoh 2.2 Plus and Bio-Rad Variant.

Cited by 57 publications

References 12 publications

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Current controversies in the use of haemoglobin A_1c

Optimizing screening procedures for early detection of glycemic disorders

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Effects of Sample Storage Conditions on Glycated Hemoglobin Measurement: Evaluation of Five Different High Performance Liquid Chromatography Methods

Abstract: All methods either met or exceeded manufacturers' claims for stability. The CLC 385/330, Tosoh G7, and Bio-Rad Variant II high performance liquid chromatography methods showed better stability than the Tosoh 2.2 Plus and Bio-Rad Variant.

Cited by 57 publications

References 12 publications

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Current controversies in the use of haemoglobin A1c

Optimizing screening procedures for early detection of glycemic disorders

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Current controversies in the use of haemoglobin A_1c