Effects of Sheng Hua Tang on Uterine Involution and Ovarian Activity in Postpartum Dairy Cows

Abstract

The effects of Sheng Hua Tang (SHT) on uterine involution and ovarian activity were investigated in postpartum dairy cows. SHT (70 g) was given to dairy cows (n = 10) to evaluate its effects for five days from the first postpartum day. Postpartum cows fed with a basal diet without SHT were used as the control group (n = 10). Ultrasounds and blood tests were recorded for four weeks from postpartum day seven with a 3-d interval. The results showed that the areas and diameters of endometria were significantly (p<0.01) reduced in the group that received SHT compared to the control group on the seventh postpartum day. The group that received SHT had an intrauterine fluid volume mean of 1.2±0.6 cm3, which was significantly lower than that of the control group, 2.3±0.8 cm3 (p<0.01) on the 13th postpartum day. In addition, the uterine tension score was a mean of 1.0±0.0 in the group that received SHT, which was also significantly lower than that of the control group, 1.5±0.5 (p<0.01) on the 19th postpartum day. Taken together, the Chinese herbal medicine remedy, SHT, promoted uterine involution and ovarian activity in postpartum dairy cows.

Disastrous delayed postpartum hemorrhage after 3 days of Shenghua decoction treatment

“…In our case, delayed postpartum hemorrhage occurred after 3 days of Shenghua decoction treatment. The ingredients of Shenghua decoction include Angelicae Sinensis, Ligustici Rhizoma, Semen Persicae, Zingiberis Rhizoma , and Glycyrrhizae Radix [ 2 ]. Among these ingredients, Ligustici Rhizoma has the function of improving blood circulation and eliminating blood stasis [ 3 ].…”

“…Among these ingredients, Ligustici Rhizoma has the function of improving blood circulation and eliminating blood stasis [ 3 ]. Semen Persicae has antithrombotic effects [ 2 4 ]. Glycyrrhizae Radix is a potent antispasmodic [ 2 5 ].…”

“…Semen Persicae has antithrombotic effects [ 2 4 ]. Glycyrrhizae Radix is a potent antispasmodic [ 2 5 ]. Therefore, the above ingredients in Shenghua decoction could cause an increase in bleeding from abnormal involution of the placental site due to their antithrombotic and antispasmodic effects [ 2 3 4 5 ].…”

“…In Taiwan, many women believe that Shenghua decoction is helpful for lochial discharge and uterine recovery [ 6 ] and is helpful in health-related quality of life during the postpartum period [ 7 ]. Lee et al reported that Shenghua decoction treatment was associated with less intrauterine fluid and lower uterine tension scores in cows [ 2 ]. Nonetheless, despite the use of Shenghua decoction increasing the myoelectric activity of rabbit uterine muscles during pregnancy [ 7 ], there are no data from the postpartum period.…”

Efficacy of an herbal formula Guixiong Yimu San in preventing retained placenta and improving reproductive performance in cows

“…According to traditional Chinese veterinary medicine (TCVM) theory, blood stasis is a key factor in the pathogenesis of postpartum uterine diseases 19 , and herbal agents with blood circulation-activating activities can treat uterine disease during the early postpartum period in China 20 – 23 . GYS, modified from Sheng Hua Tang , is a classical herbal formula utilized in the therm postpartum women's care to stimulate blood circulation, increase uterine contraction, alleviate abdominal pain, and expel lochia 24 .…”