Effects of Short-Period Whole-Body Vibration of 20Hz on Selected Blood Biomarkers in Wistar Rats

Abstract

There is a growing interest in the use of vibration generated by oscillating/vibratory platforms - also known as whole-body vibration (WBV) - for achieving therapeutic, preventative and/or physical performance goals. This study investigated the effects of vibration generated by an oscillating platform on the concentration of blood biomarkers in rats. Wistar rats (n = 8) were divided in 2 groups, sedated and individually positioned on an oscillating platform. The experimental group (EG) was subjected to vibrations of 20 Hz for one min per day for one week while the control group (CG) experienced no vibration. Samples of heparinized whole blood were drawn by cardiac puncture for biochemical analysis. Concentrations of total cholesterol, triglycerides, HDL, LDL, VLDL, glucose, CK, albumin, alkaline phosphates, TGP, TGO, γGT, lipase, amylase, urea and creatinine were determined. White blood cell count and a platelet hemogram were also performed. Following seven sessions of exposure to the vibration, a significant (P < 0.05) reduction in γGT, VLDL and leukocytes was found. A weekly 1-min/day exposure of 20 Hz vibration can was shown to alter the concentrations of selected blood biomarkers in rats. The action mechanism associated with these effects seems highly complex, but the findings might contribute to the understanding of these mechanisms related to the exposure to 20 Hz vibration.

Effect of Mechanical Vibration Generated in Oscillating/Vibratory Platform on the Concentration of Plasma Biomarkers and on the Weight in Rats.

“…Naghii et al (2011) have not found alterations on the concentration of these biomarkers. Monteiro et al (2015) have reported no significant alteration in the concentration of total cholesterol, triglycerides, HDL, LDL and VLDL, although a significant reduction in VLDL after 1-min/day exposure of 20 Hz vibration during seven days was observed.…”

“…This may however be because this study was conducted in healthy animals. Monteiro et al (2015) have reported a no significant alteration in the glucose after 1-min/day exposure of 20 Hz vibration. Di Loreto et al (2004) reported in their study that vibration at 30 Hz of frequency resulted in a slight reduction in blood glucose levels in patients with DM-2.…”

“…No significant differences between the experimental groups and control group were found for either total blood counts or selected immunological parameters. Monteiro et al (2015) have reported a significant reduction in gamma glutamyl transferase (γGT), very low-density lipoprotein (VLDL) and leukocytes after 1-min/day exposure of 20 Hz vibration. Rubin et al (2007) have reported that 15 weeks of brief, daily exposure to high-frequency mechanical signals, induced at a magnitude well below that which would arise during walking, inhibited adipogenesis by 27% in C57BL/6J mice.…”

Effect of a Short Period Whole Body Vibration With 10 Hz on Blood Biomarkers in Wistar Rats

“…The rats were sedated (sodium thiopental, 50mg/kg/weight) and divided in two groups. They were positioned one on each side of the platform and had its head fixed with tape resting on a makeshift gauze pillow, and there was a small difference in the peak-to-peak displacements that were 1.5 and 3.8 mm considering the center line of the rats (Monteiro et al, 2015). The animals of the EG were submitted to 10 Hz for one min per day for one week (seven sessions) with a total of seven minutes of WBV.…”

“…In consequence, they were submitted to the same stress conditions. In this investigation was followed the protocol previously published by Monteiro et al (2015).…”