Effects of subgingival air-polishing with trehalose powder on oral biofilm during periodontal maintenance therapy: a randomized-controlled pilot study

Abstract

Background: This pilot study was part of a larger study which compared the effect of subgingival air-polishing using trehalose powder with sonic scaling on clinical parameters during supportive periodontal therapy. Within this microbiological part of the investigation subgingival samples were taken from 10 participants to analyze the survival of different bacterial species after the two different treatments as a proof of principle. Methods: In 10 participants two non-adjacent, single-root teeth requiring treatment (PD =5 mm with bleeding on probing (BOP) or > 5 mm) were selected following a split-mouth design and were treated either with a sonic scaler or air-polishing device and trehalose powder. For persistent pockets (PD =4 mm and BOP or > 4 mm), treatment was repeated after 3 months. Subgingival biofilm samples were taken at baseline (BL), subsequently and three and six months after treatment. After determination of the bacterial counts (TBL), isolated bacteria were identified by MALDI-TOF-MS. If unsuccessful, PCR and 16S rDNA sequencing were performed. Results: In both treatment groups, TBL decreased immediately after treatment remaining at a lower level. This confirms the findings of the larger study regarding clinical parameters showing a comparable effect on PD, BOP and CAL. Immediately after treatment, the diversity of detected species decreased significantly more than in the sonic group (p = 0.03). After 3 months, the proportion of Gram-positive anaerobic rods was lower in the airpolishing group (powder/ sonic 7%/ 25.9%, p = 0.025). Also, there was a greater reduction of Gram-negative aerobic rods for this group at this time (air-polishing/ sonic − 0.91 /-0.23 Log10 cfu/ ml, p = 0.020). Conclusion: Within the limitations of this study air-polishing and sonic treatment seem to have a comparable effect on the subgingival oral biofilm during supportive periodontal treatment. Trial registration: The study was registered in an international trial register (German Clinical Trial Register number DRKS 00006296) on 10th of June 2015. HTML&TRIAL_ID = DRKS00006296.

Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

“…Reviewing the existent literature there are only limited data on the e cacy of using air-polishing with erythritol during periodontal therapy. Some studies focused on the effects of air-polishing with erythritol during the supportive periodontal therapy [10,12,24,25]. Comparable results regarding BOP and PD as well as residual pockets ≥4mm were reported for the nozzle use with erytritol and hand instruments, an advantage might be the low abrasiveness [10,12].…”

Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy: a randomized clinical trial

“…Reviewing the existent literature there are only limited data on the efficacy of using air-polishing with erythritol during periodontal therapy. Some studies focused on the effects of air-polishing with erythritol during the supportive periodontal therapy [ 10 , 12 , 24 , 25 ]. Comparable results regarding BOP and PD as well as residual pockets ≥ 4 mm were reported for the nozzle use with erythritol and hand instruments, an advantage might be the low abrasiveness [ 10 , 12 ].…”

Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

“…Reviewing the existent actual literature there are only limited data on the e cacy of using air-polishing with erythritol during periodontal therapy. Some studies focused on the effects of air-polishing with erythritol during the supportive periodontal therapy (Hägi et al 2013, Hägi et al 2015, Kruse et al 2020, Müller 2014. Comparable results regarding BOP and PD as well as residual pockets ≥ 4 mm were reported for the nozzle use with erytritol and hand instruments, an advantage might be the low abrasiveness (Hägi, 2013(Hägi, , 2015.…”