“…Elimination of nickel and beryllium was achieved in 2007 with the Ti-Zr-Cu-Pd family of compositions, based on a (Ti-Zr) 50 (Cu-Pd) 50 concept and subsequent small additions of elements like Sn, Si, Ta, Nb, Co, or In [ 17 , 22 , 23 , 24 , 25 , 26 , 27 , 28 ]. This new approach is an important accomplishment allowing fabrication of components with critical dimensions up to 10 mm, simultaneously with elimination of nickel, which is one of the most allergenic elements, as well as beryllium, with its high cytotoxic effects.…”