Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly

Pfrimer, Karina; Ferriolli, Eduardo; Takeuchi, Paula Lumy; Salles, Márcia Saladini Vieira; Saran-Netto, Arlindo; Zanetti, Marcus Antônio; Roma-Junior, Luiz C.; Braga, Cristiane Giffoni; Domenici, F; Valim, Yara Maria Lucisano; Paschoalato, Adriana Balbina Paoliello; Marchi, Larissa Fávaro; Azzolini, Ana Elisa Caleiro Seixas; Donadi, Eduardo Antônio; Martinez, Edson Zangiacomi; Vannucchi, Hélio

doi:10.1002/mnfr.201700307

Cited by 11 publications

(10 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fortification of milk nutrients is usually achieved by the direct addition of the nutrients to the final product, with this technique recently shown to enhance vitamin E, selenium, and levels of different FA in milk (Leduc et al, 2017;Meignan et al, 2017;Pfrimer et al, 2018). An alternative to the direct addition of nutrients can be achieved via natural means such as modification of the diet of the cows or biofortification, which can reduce the possibility of overfortifying milk, thus reducing the risk of potential health problems from overconsumption of the added macronutrients.…”

Section: Introductionmentioning

confidence: 99%

Modification of the sterol profile in milk through feeding

Duong

Strobel

Buddhadasa

et al. 2019

Journal of Dairy Science

View full text Add to dashboard Cite

The fortification of milk with phytosterols is an increasingly common practice to enhance the sterol profile and offer consumers potential health benefits. This study investigated whether cattle feed can influence the profile of phytosterols and cholesterol in the milk produced as an alternative to direct fortification of milk. Five experiments were performed using feeds commonly used by Australian dairy farmers and selected formulated rumen-protected feeds. Statistical significances were observed for some individual plant sterols and cholesterol in milk under these differing feeding regimens compared with the respective controls. In the case of the phytosterols, where the daily recommended consumption is typically 2 g per day, the total phytosterols were <0.12 mg/100 mL of milk. An experiment using a rumen-protected feed with high phytosterol levels suggested a decreased transfer of cholesterol to the milk by as much as 20%, although further work is required to confirm these preliminary results. Overall, the study suggests that different feeding practices have minimal effect on the resulting sterol profile of the milk.

show abstract

Section: Introductionmentioning

confidence: 99%

Modification of the sterol profile in milk through feeding

Duong

Strobel

Buddhadasa

et al. 2019

Journal of Dairy Science

View full text Add to dashboard Cite

show abstract

“…Selenium is important in adults and elderly people for the stimulation of both acquired and innate immunity attributed to selenium antioxidant properties. Selenium is known to improve and enhance immunity of cells by increasing production of cytokines specifically to enhance production of interferon gamma (IFN-γ) and interleukin 10 (IL10) production which mitigates against aging-induced effects, as well as inflammatory effects in the immune system [12]. Aging affects lifespan with low serum selenium levels found to promote age-related diseases such as tumors, cardiovascular and neuropsychiatric diseases as well as aging of the skin [34].…”

Section: Adulthood and The Elderlymentioning

confidence: 99%

“…Therefore, adequate daily intake is crucial. For example, copper is essential for maintaining cognitive function in elderly people and selenium plays an important role in boosting the immune system [11,12]. Additionally, these microminerals can prevent deterioration of age-related diseases (i.e., the intravenous iron helps in heart failure patients) [13].…”

Section: Introductionmentioning

confidence: 99%

Dietary Micronutrients from Zygote to Senility: Updated Review of Minerals’ Role and Orchestration in Human Nutrition throughout Life Cycle with Sex Differences

et al. 2021

View full text Add to dashboard Cite

Micronutrients such as selenium, fluoride, zinc, iron, and manganese are minerals that are crucial for many body homeostatic processes supplied at low levels. The importance of these micronutrients starts early in the human life cycle and continues across its different stages. Several studies have emphasized the critical role of a well-balanced micronutrient intake. However, the majority of studies looked into or examined such issues in relation to a specific element or life stage, with the majority merely reporting the effect of either excess or deficiency. Herein, in this review, we will look in depth at the orchestration of the main element requirements across the human life cycle beginning from fertility and pregnancy, passing through infancy, childhood, adolescence, and reaching adulthood and senility, with insight on the interactions among them and underlying action mechanisms. Emphasis is given towards approaches to the role of the different minerals in the life cycle, associated symptoms for under- or overdoses, and typical management for each element, with future perspectives. The effect of sex is also discussed for each micronutrient for each life stage as literature suffice to highlight the different daily requirements and or effects.

show abstract

“…A tríade de inflamação, estresse oxidativo e envelhecimento das células imunes representa importantes mecanismos que podem ser melhorados por meio da nutrição adequada (14,15) . A microbiota intestinal pode ter um impacto na deterioração relacionada ao envelhecimento por sua atividade nutricional e imunomoduladora (16) .…”

Section: Nutriçãounclassified

Pandemia Da Covid-19 E Idosos Como População De Risco: Aspectos Para Educação Em Saúde

2020

View full text Add to dashboard Cite

Objetivo: discorrer sobre a fisiopatogênese da COVID-19 e vulnerabilidade clínica do indivíduo idoso, além de aspectos relevantes para promoção da saúde e do autocuidado da pessoa idosa.Desenvolvimento: realizou-se investigação dos temas em plataformas científicas de busca, além de documentos oficiais da Organização Mundial de Saúde e do Ministério da Saúde. O vírus causador da COVID-19 apresenta, fundamentalmente, complicações respiratórias. O processo de senescência do aparelho respiratório torna o idoso vulnerável tanto para infecção, como para agravamento e letalidade. Atividade física, nutrição adequada, qualidade do sono, exposição ao sol, saúde mental e espiritualidade permitem a preservação e promoção da saúde dos sistemasimunológicos e respiratórios, e devem ser estimuladas para o autocuidado do idoso.Conclusão: esta reflexão contribui para orientação de profissionais de saúde no cuidadogerontológico de enfermagem, no procedimento de educação em saúde dos aspectos referentes à prevenção e autocuidado dos idosos, como população de risco paraC OVID-19.

show abstract

Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly

Abstract: Overall, as compared to C, milk biofortification was associated with stabilization of the activity of alternative complement pathway and the neutrophils burst, and modulated different cytokines levels.

Cited by 11 publications

References 29 publications

Modification of the sterol profile in milk through feeding

Modification of the sterol profile in milk through feeding

Dietary Micronutrients from Zygote to Senility: Updated Review of Minerals’ Role and Orchestration in Human Nutrition throughout Life Cycle with Sex Differences

Pandemia Da Covid-19 E Idosos Como População De Risco: Aspectos Para Educação Em Saúde

Contact Info

Product

Resources

About