Effects on haematology parameters during cold storage and cold transport of rat and dog blood samples

Hayashi, Yutaka; Matsuzawa, Toshiaki; Unno, Takashi; Morita, Nobuto; Nomura, Mamoru

doi:10.1007/bf02044141

Cited by 10 publications

(3 citation statements)

References 12 publications

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“…The MCV was mostly increased, as in previous studies,2,4,6 the mean increase being almost the same as in an earlier study, ie, about 3 to 4 fL after 24 hours at room temperature 7. In this study, the increase in MCV led to misclassification of almost 20% of dogs at 24 hours and 45% at 48 hours, with normocytic RBCs erroneously classified as macrocytic.…”

Section: Discussionsupporting

confidence: 87%

“…Most of the studies were performed on limited numbers of samples or did not include samples from dogs with severe hematologic abnormalities (Table 1). 2–7 The main observations in stored canine blood were increases in HCT and WBC count, decreases in platelet count, and no change in RBC count or hemoglobin (Hgb) concentration.…”

Section: Survey Of Literature Regarding the Stability Of Cbc Analytesmentioning

confidence: 99%

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Stability of selected hematology variables in canine blood kept at room temperature in EDTA for 24 and 48 hours

Médaille¹,

Briend‐Marchal²,

Braun³

2006

Veterinary Clinical Pathol

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Section: Discussionsupporting

confidence: 87%

Section: Survey Of Literature Regarding the Stability Of Cbc Analytesmentioning

confidence: 99%

Stability of selected hematology variables in canine blood kept at room temperature in EDTA for 24 and 48 hours

Médaille¹,

Briend‐Marchal²,

Braun³

2006

Veterinary Clinical Pathol

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“…Refrigeration . Reports on effects of refrigeration on hematology results are controversial, for example, for WBC in dogs . The canine platelet count has been reported stable for 3 days, however in canine blood, platelet clumping was enhanced in refrigerated specimens …”

Section: Technical Preanalytic Factorsmentioning

confidence: 99%

The preanalytic phase in veterinary clinical pathology

Braun

Bourgès‐Abella

Geffré

et al. 2014

Veterinary Clinical Pathol

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This article presents the general causes of preanalytic variability with a few examples showing specialists and practitioners that special and improved care should be given to this too often neglected phase. The preanalytic phase of clinical pathology includes all the steps from specimen collection to analysis. It is the phase where most laboratory errors occur in human, and probably also in veterinary clinical pathology. Numerous causes may affect the validity of the results, including technical factors, such as the choice of anticoagulant, the blood vessel sampled, and the duration and conditions of specimen handling. While the latter factors can be defined, influence of biologic and physiologic factors such as feeding and fasting, stress, and biologic and endocrine rhythms can often not be controlled. Nevertheless, as many factors as possible should at least be documented. The importance of the preanalytic phase is often not given the necessary attention, although the validity of the results and consequent clinical decision making and medical management of animal patients would likely be improved if the quality of specimens submitted to the laboratory was optimized.

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Smith¹,

Jarecki²

2011

Atlas of Comparative Diagnostic and Experimental Hematology

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Effects on haematology parameters during cold storage and cold transport of rat and dog blood samples

Cited by 10 publications

References 12 publications

Stability of selected hematology variables in canine blood kept at room temperature in EDTA for 24 and 48 hours

Stability of selected hematology variables in canine blood kept at room temperature in EDTA for 24 and 48 hours

The preanalytic phase in veterinary clinical pathology

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