Effects on Honey dates Amla mix on level of Fatigue on Iron Deficiency Anaemia among Adolescent Girls at Selected Setting

Bhuvaneswari, G.; Kerubhamani, Hepshibha; Gowri, P. Mangala

doi:10.5958/0974-360x.2018.00613.3

Cited by 5 publications

(1 citation statement)

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“…18 Pharmacological active constituents present in Amla provide immunity, give relief from bleeding disorder and when mixed with honey date provide relief from iron deficiency anemia in adolescent girls. 19 Amla also act as antioxidant, antibacterial, anti-aging and as a natural blood purifier as a skin health care products. 20 Honey is made by honey bees from fruit nectar.…”

Section: Methodsmentioning

confidence: 99%

A Comparative Evaluation of Various Therapies of Synthetic Drugs with Amla and Honey Combination for the Treatment of Gastroesophageal Reflux Disease

Mazumder¹,

Kumar²,

Das³

2023

Ind. J. Pharm. Edu. Res.

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Background: Gastroesophageal Reflux Disease (GERD) is disorder of oesophagus that causes ulcer and erosion. Materials and Methods: A comparison based on the in vivo study was carried out to determine the therapeutic efficacy of herbal formulation using Amla and Honey in combination with Pantoprazole and Rebamipide for the treatment of GERD. The effects of all above mentioned medications were also checked on intestinal motility. In vitro studies were carried out to determine the antispasmodic activity of Amla and Honey in comparison to acetylcholine by isolated rat ileum. In pylorus ligation GERD model, mono-therapy was performed by giving herbal formulation of Amla and Honey. In combination therapy Pantoprazole and Rebamipide, Amla and Honey with Pantoprazole and Rebamipide were given and their therapeutic efficacy was observed at the ends of 14 days. In charcoal meal motility test the distance travelled by charcoal in intestine was measured. Results and Discussion: Combination therapy have highest therapeutic efficacy in comparison to mono-therapy of natural combination of Amla and Honey against Pantoprazole and Rebamipide. In vitro antispasmodic activity revealed that Amla and Honey formulation decreased the contractility pattern in concentration dependent manner against acetylcholine. In charcoal meal motility test highest intestinal motility were observed in Amla and Honey and can be given in GERD for easily digestion of food from stomach. Conclusion: Herbal combination of Amla and Honey in comparative evaluation decreases the Gastroesophageal reflux disease, intestinal mobility, and show anti-spasmodic activity in isolated rat's ileum. However, these combinations serve as a more potential agent for decreasing all the factors responsible for the reflux disease.

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Section: Methodsmentioning

confidence: 99%

A Comparative Evaluation of Various Therapies of Synthetic Drugs with Amla and Honey Combination for the Treatment of Gastroesophageal Reflux Disease

Mazumder¹,

Kumar²,

Das³

2023

Ind. J. Pharm. Edu. Res.

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A Comparative Study on Mono-therapy and Combination Therapy of Additive Drugs (Rebamipide and Pantoprazole) with Amla and Honey combination for the Treatment of Gastroesophageal Reflux Disease and Intestinal motility

Mazumder

Kumar

Das

et al. 2022

RJPT

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Gastroesophageal reflux disease (GERD) is digestive disorder of oesophagus. Reflux of food damage oesophagus and cause oesophageal ulcer and erosion. The treatment strategy starts by giving natural formulation and synthetic drugs. A comparison based on In-vivo study was carried out to determine the therapeutic efficacy of herbal formulation using Amla and Honey in combination with Pantoprazole and Rebamipide for the treatment of GERD, The effects of all above mentioned medication was also checked on intestinal motility. In vitro studies were carried out to determine the antispasmodic activity of Amla and Honey in comparison to acetylcholine by isolated rat ileum. In pylorus ligation GERD model mono-therapy was performed by giving herbal formulation of Amla and Honey. In combination therapy Pantoprazole and Rebamipide, Amla, Honey with Pantoprazole and Rebamipide were given and their therapeutic efficacy was observed at the ends of 14 days. In charcoal meal motility test the distance travelled by charcoal in intestine was measured. At the end of study it was concluded that combination therapy have highest therapeutic efficacy in comparison to mono-therapy of natural combination of Amla and Honey against Pantoprazole and Rebamipide. In In-vitro antispasmodic activity Amla and Honey formulation decreased the contractility pattern in concentration dependent manner against acetylcholine. In charcoal meal motility test highest intestinal motility were observed in Amla and Honey and can be given in GERD for easily digestion of food from stomach.

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The effect of Pauttika honey and Orlistat on Histological Evaluations of Liver, Kidney and Adipose tissue in high-fat diet-induced Obesity in Charles Foster male rats

Veena,

Verma,

Ghosh Kar

et al. 2023

RJPT

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Background: Honey's weight-reducing, hypoglycemic, hypolipidemic, and hepatoprotective properties have been demonstrated. Orlistat, a FDA-approved medicine for obesity control, have adverse effects. Honey is a rich source of nutrients with antiobesity (Medohara) and sacrificant (lekhan) qualities, which help to reduce Pitta, Kapha, and Medas; is suggested in diabetic control. In this study, Pauttika honey is studied against biochemical markers and histological manifestations in visceral organs of high-fat diet-induced obese Charles Foster rats. No research was identified on the effect of Pauttika honey (a specific kind of honey described in Ayurveda) on obese rats' liver, kidney, and adipose tissues. An article on the biochemical analysis of this honey (new and old ) has been already published. Objective: Evaluate the effects of Pauttika honey and Orlistat on high-fat diet-induced fatty changes in obese Charles Foster rats. Methods: This study examines male Charles Foster rat histopathological alterations. 24 male Charles Foster rats with a mean weight of 181±15gm were divided into four groups of six. High-fat diets (HFD) for 8 weeks caused obesity in three groups. After that, Pauttika honey mixed with equal amounts of water (Madudaka) and Orlistat were given to two groups for 6 weeks. The HFD was maintained throughout the experiment, except in the NC group, which ate standard chow. On the last day of the 14th week, the animals were sacrificed and the Liver, kidney, heart, spleen, and lungs were weighed. The liver, kidney, and adipose tissues were preserved in 10% formalin for histopathology. Results: Rats’ relative organ weight (ROW) showed no significant alterations. Histology of liver tissues showed micro and macro steatosis and ballooning degeneration in the HFD group, while Pauttika honey and orlistat both showed improvement in fatty changes but it was better in the Pauttika group. Kidney and adipose tissues showed no morphological or structural abnormalities. Conclusion: This study shows that Pauttika honey mixed with water (Madudaka) protects the livers of obese rats. Histology suggests Pauttika honey is efficacious and safer than Orlistat for HFD-induced obesity.

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Effects on Honey dates Amla mix on level of Fatigue on Iron Deficiency Anaemia among Adolescent Girls at Selected Setting

Cited by 5 publications

References 0 publications

A Comparative Evaluation of Various Therapies of Synthetic Drugs with Amla and Honey Combination for the Treatment of Gastroesophageal Reflux Disease

A Comparative Evaluation of Various Therapies of Synthetic Drugs with Amla and Honey Combination for the Treatment of Gastroesophageal Reflux Disease

A Comparative Study on Mono-therapy and Combination Therapy of Additive Drugs (Rebamipide and Pantoprazole) with Amla and Honey combination for the Treatment of Gastroesophageal Reflux Disease and Intestinal motility

The effect of Pauttika honey and Orlistat on Histological Evaluations of Liver, Kidney and Adipose tissue in high-fat diet-induced Obesity in Charles Foster male rats

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