Efficacy and safety of standardized Ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial

Kaur, Jasbir; Seshadri, Sujit; Golla, Krishna Hasitha; Sampara, Prasanthi

doi:10.1016/j.jveb.2022.03.002

Cited by 7 publications

(4 citation statements)

References 30 publications

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“…These first minutes are important to monitor as the period during which dogs with some health issues are likely to display abnormal behavioral patterns [ 78 , 79 ]. Dog 1 in Figure 8 a covered a wide area of the room in a short period of time, indicating a high level of restlessness and movement, which are indicators of stress and anxiety [ 80 , 81 ]. Figure 8 b shows how dog 2 spent that time near the exit from where its owner left, which is considered a normal behavior of attachment that healthy dogs commonly display [ 79 ].…”

Section: Resultsmentioning

confidence: 99%

Behavior-Based Video Summarization System for Dog Health and Welfare Monitoring

Atif

Lee

Park

et al. 2023

Sensors

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The popularity of dogs has been increasing owing to factors such as the physical and mental health benefits associated with raising them. While owners care about their dogs’ health and welfare, it is difficult for them to assess these, and frequent veterinary checkups represent a growing financial burden. In this study, we propose a behavior-based video summarization and visualization system for monitoring a dog’s behavioral patterns to help assess its health and welfare. The system proceeds in four modules: (1) a video data collection and preprocessing module; (2) an object detection-based module for retrieving image sequences where the dog is alone and cropping them to reduce background noise; (3) a dog behavior recognition module using two-stream EfficientNetV2 to extract appearance and motion features from the cropped images and their respective optical flow, followed by a long short-term memory (LSTM) model to recognize the dog’s behaviors; and (4) a summarization and visualization module to provide effective visual summaries of the dog’s location and behavior information to help assess and understand its health and welfare. The experimental results show that the system achieved an average F1 score of 0.955 for behavior recognition, with an execution time allowing real-time processing, while the summarization and visualization results demonstrate how the system can help owners assess and understand their dog’s health and welfare.

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Section: Resultsmentioning

confidence: 99%

Behavior-Based Video Summarization System for Dog Health and Welfare Monitoring

Atif

Lee

Park

et al. 2023

Sensors

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“…Kaur et al. ( 2022 ) studied the effect of ashwagandha on reducing stress and anxiety in domestic dogs aged 3–8 years and reported that ashwagandha was associated with significant reductions in urine cortisol–creatinine ratio, signs of fear and anxiety and pain interference. Priyanka et al.…”

Section: Discussionmentioning

confidence: 99%

“…The dog owners were instructed to give the powder as per animal body weight by uniformly mixing in the regular meal. The dose was selected based on earlier published literature (Kaur et al., 2022 ).…”

Section: Methodsmentioning

confidence: 99%

Effects of ashwagandha (Withania somnifera) root extract on aging‐related changes in healthy geriatric dogs: A randomized, double‐blinded placebo‐controlled study

Bharani,

Devarasetti,

Carey

et al. 2024

Veterinary Medicine & Sci

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Background and aimThis study aimed to explore the clinical potential of Withania somnifera/ashwagandha root extract (ARE) to mitigate age‐related changes in healthy geriatric dogs. We hypothesized that ARE can reduce the effects of advancing age, including physiological changes, immune response decline and susceptibility to diseases, by its immunomodulatory effects.MethodsA randomized, double‐blind, placebo‐controlled trial was conducted in Telangana, India, from July 2022 to September 2022. Twenty apparently healthy dogs, aged 8 years or older, were enrolled. The dogs were divided into two groups to receive ARE (15 mg/kg, once daily, orally) or a placebo control. Various parameters, including serum cortisol levels, haematological profiles, biochemical markers, antioxidant indicators and anti‐inflammatory responses, were assessed at the initiation of study, day 30, and day 60.ResultsThe erythrocyte count and haemoglobin levels were significantly increased with ARE (p < 0.001), whereas leukocyte count decreased (p < 0.05). Moreover, significant decreases in important markers of liver function (alanine aminotransferase, aspartate aminotransferase, albumin and globulin; p < 0.001 at day 60), as well as kidney function markers (creatinine and blood urea nitrogen; p < 0.001 at days 30 and 60), were observed in ARE‐treated dogs compared to the placebo control group. In addition, the levels of markers of oxidative stress (superoxide dismutase, catalase, glutathione and malondialdehyde) were significantly modulated by ARE intervention, indicating strong antioxidant effects. Interestingly, serum cortisol levels reduced significantly with ARE (p < 0.001). Compared to baseline, ARE significantly decreased key inflammatory markers, including interferon‐γ, tumour necrosis factor‐α, nuclear factor kappa light chain enhancer of activated B cells and interleukin‐10 (p < 0.001) levels at day 60.ConclusionIn conclusion, the findings of this study suggest that ARE has adaptogenic properties in healthy geriatric dogs by improving haematological and biochemical profiles, enhancing antioxidant defence, reducing stress and modulating inflammatory responses.

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“…Diversos tratamentos têm sido propostos tanto no âmbito comportamental quanto medicamentoso, como o enriquecimento ambiental (Karagiannis et al, 2015;Shin & Shin, 2016;Takeuchi et al, 2000), o uso de antidepressivos, como a fluvoxamina (Bazin & Desmarchelier, 2022) combinada ou não com clomipramina ou clonidina (Hausman et al, 2009;Landsberg et al, 2008;Ogata & Dodman, 2011), bem como medicamentos naturais como o Plactiplantibacillus plantarum PS128 (Yeh et al, 2022), o fitoterápico Ashwagandha (Kaur et al, 2022), tratamento com homeopáticos (Von Ancken & Coelho, 2018) e acupuntura (Kontogianis et al, 2019). O prognóstico nem sempre é favorável pois demanda muito comprometimento do tutor.…”

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Tratamiento homeopático para la ansiedad por separación post-Covid-19 en perros. Reporte de un caso

Andena¹,

Barberini²,

Baía³

2023

Pubvet

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A Síndrome da Ansiedade de Separação (SAS) em cães tem sido um dos distúrbios mais recorrentes pós-pandemia do Covid 19, apresentando como sinais clínicos comportamento destrutivos, vocalização excessiva, urinar e defecar em locais inadequados, vômitos, ansiedade, frustração, pânico, medo, tédio, agressividade. O tratamento normalmente inclui enriquecimento ambiental, treinamento, medicação alopática com antidepressivos, ansiolíticos e tratamentos integrativos como o Plactiplantibacillus plantarum PS128, o fitoterápico Ashwagandha, homeopatia e acupuntura. Apresentamos o relato de um caso clínico de um cão macho, fox paulistinha que apresentou ansiedade de separação após retorno dos tutores às atividades pós isolamento causado pela pandemia de covid-19. O cão também apresentava convulsões a cada 3-4 meses e doença periodontal grau 3-4. Após repertorização instituiu-se tratamento Arsenicum album 30 CH SID por 30 dias para a ansiedade de separação; para a doença periodontal Mercurius solubilis 6CH TID, por 30 dias, e para as crises convulsivas Cicuta virosa 200 CH uma vez por semana, até novas orientações. Após retorno de 30, 60, 90 e 120 dias observou-se melhora importante no comportamento de ansiedade, como também espaçamento das crises convulsivas. Os medicamentos homeopáticos instituídos neste caso clínico demonstraram efetividade para o tratamento dos distúrbios comportamentais, bem como dos sinais físicos presentes.

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Efficacy and safety of standardized Ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial

Cited by 7 publications

References 30 publications

Behavior-Based Video Summarization System for Dog Health and Welfare Monitoring

Behavior-Based Video Summarization System for Dog Health and Welfare Monitoring

Effects of ashwagandha (Withania somnifera) root extract on aging‐related changes in healthy geriatric dogs: A randomized, double‐blinded placebo‐controlled study

Tratamiento homeopático para la ansiedad por separación post-Covid-19 en perros. Reporte de un caso

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