Efficacy of azithromycin compared with spiramycin in the treatment of odontogenic infections

Bue, A.M. Lo; Sammartino, R; Chisari, G; Gismondo, Maria Rita; Nicoletti, Giuseppe

doi:10.1093/jac/31.suppl_e.119

Cited by 22 publications

(3 citation statements)

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“…23 In this study it proved to be superior to spiramycin, in patients with more severe disease. Furthermore, the frequency of microbial resistance was lower with azithromycin (18%) compared with spiramycin (26%).…”

Section: Therapeutic Usesmentioning

confidence: 56%

“…[23][24][25][26][27][28][29] Azithromycin shows good bacteriostatic in-vitro activity against a wide variety of micro-organisms found in the mouth, 30 with a broad spectrum of activity towards anaerobic bacteria as well as Gram-negative bacilli. 31 One of the problems associated with using systemic antimicrobials for the adjunctive management of odontogenic infections is patient compliance.…”

Section: Therapeutic Usesmentioning

confidence: 99%

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Azithromycin and dentistry — a useful agent?

Addy

Martin²

2004

Br Dent J

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Section: Therapeutic Usesmentioning

confidence: 56%

Section: Therapeutic Usesmentioning

confidence: 99%

Azithromycin and dentistry — a useful agent?

Addy

Martin²

2004

Br Dent J

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“…Penicillin V was less effective on isolates in dental infections compared to aminopenicillins in combination with ßlactamase inhibitors (Vogel et al 2002). Spiramycin should be avoided due to a relatively poor resorption rate and efficiency compared to newer macrolides (Lo Bue et al 1993). Regarding treatment length a prolonged prophylactic antibiotic medication could be harmful by creating resistant strains of bacteria (Longman & Martin 1991).…”

Section: Amoxicillinmentioning

confidence: 99%

Antibiotics in third molar surgery

Vlcek,

Razavi,

Kuttenberger

2014

Swiss Dent. J. SSO

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The aim of this survey was to assess the knowledge and practice of Swiss dentists focusing on the use of antibiotics in prophylactic surgical removal of lower wisdom teeth. A postal survey was conducted among all 3288 dentists who are members of the Swiss Dental Society (SSO) representing nearly all dentists in Switzerland. The questionnaire consisted of 13 questions with mostly multiple-choice answers. Demographic profile, surgical experience, the use of antibiotics, and wound management, i.e. wound closure and the use of mouth rinse were assessed. A response rate of 55% was obtained. Most Swiss dentists perform surgical extractions in their practices. Of all dentists, 18.6% used antibiotics routinely, but a large variation was found comparing the three linguistic regions of Switzerland with the highest prescription rate of 48% in the French-speaking south-west of Switzerland. Fifty-two percent of dentists prescribed amoxicillin in a dose of 750 mg. Most often three daily doses were prescribed (47%). A postoperative regime was prescribed by 54.4% of dentists. French language (p=0.003), graduation from the university of Geneva (p=0.007), foreign diplomas (p<0.001), and dentists with diplomas awarded from 2001-2006 (p=0.004) showed a highly significant correlation with the use of antibiotics. In Switzerland, prophylactic antibiotics are used in third molar surgery. Antibiotic prescription however largely depends on geographical situation and dentist profiles. The assessment of antibiotic use in private practices is important in the light of growing evidence that antibiotic overuse may lead to development of multiresistant bacterial strains. In a second part results regarding wound management and mouth rinse will be presented.

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2009

Orale Antibiotika in Klinik Und Praxis

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Efficacy of azithromycin compared with spiramycin in the treatment of odontogenic infections

Cited by 22 publications

References 0 publications

Azithromycin and dentistry — a useful agent?

Azithromycin and dentistry — a useful agent?

Antibiotics in third molar surgery

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