Efficacy of PET/CT in the characterization of solid or partly solid solitary pulmonary nodules

The value of 18F-FDG-PET/CT in the differential diagnosis of solitary pulmonary nodules in areas with a high incidence of tuberculosis

“…This result is in agreement with those reported elsewhere. Jeong et al [7,23] compared the application of CT, PET, and PET/CT with SPNs and reported that the sensitivity of PET/CT was higher than that of CT. Through a comparison of the application in 42 patients with SPN between CT, PET, and PET/CT, Shanna et al [10] reported that the sensitivities of CT, PET, and PET/CT were 93, 69, and 97%, respectively, and the specificities were 31, 85, and 85%, respectively, which indicated that the sensitivity and specificity of PET/CT were higher than that of CT and PET alone.…”

“…In one study [7], PET/CT was shown to be better in terms of SPN characterization by providing higher sensitivity and accuracy than the helical dynamic CT. However, there have been few studies comparing the efficacy of PET/CT for nodule characterization with the use of CT alone or PET alone in an area where TB has a high prevalence.…”

Evaluation of Individuals With Pulmonary Nodules: When Is It Lung Cancer?

“…Of three studies that compared dedicated PET scan with integrated PET/CT scan for pulmonary nodule characterization ( Table S9 ), integrated PET/CT scan was slightly more accurate in two of them, but none of the studies compared integrated PET/CT scan with standard care (side-by-side interpretation of dedicated PET scan and dedicated CT scan). [62][63][64] Although we view nodule characterization and lung cancer staging as separate indications for PET scanning, we favor PET scan over other functional imag ing modalities for nodule characterization in part because PET scan often provides additional information about stage among individuals with malignant nodules. Recommendations about the use of PET scanning for staging are described by Silvestri et al 65 in the "Methods for Staging Non-small Cell Lung Cancer" article in the ACCP Lung Cancer Guidelines.…”

SPECT/CT stabilizes the interpretation of somatostatin receptor scintigraphy findings: a retrospective analysis of inter-rater agreement

“…For example, Plathow et al [17] comparing PET and PET/CT with FDG in 54 patients with limited malignant pleural mesothelioma, found that the inter-rater agreement was improved to kappa = 1 in PET/CT compared to j = 0.9 in PET only. In contrast, Jeong et al [18] reported that in the characterization of solid or partly solid solitary pulmonary nodules inter-rater agreement was lower in PET/CT (j = 0.64-0.78) than in PET with FDG (j = 0.78-0.90). The authors did not offer an explanation for this somewhat unexpected finding.…”