Efficiency of phage therapy: methodological features of a systematic review

Saperkin, N.V.; Квашнина, Д. В.; Kovalishena, O. V.; Scholten, R. J. P. M.; Ruizendaal, Esmée

doi:10.21145/2499-9954-2018-4-129-132

Cited by 2 publications

(2 citation statements)

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“…В последние два десятилетия внимание к бактериофагам вновь активизировалось [41,42]. Проводятся исследования по использованию фагов для лечения кишечных инфекций, оценивается их безопасность и клиническая эффективность [43].…”

Section: современный потенциал терапии и профилактики на основе фаговunclassified

Personalized therapy with bacteriophages of digestive diseases

Гончар

Ермоленко²,

Скрипченко

2022

jour

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Current insights into the close relationship between human health and the gut microbiota, as well as recent advances in molecular biology suggesting a significant role for gut viromas, have encouraged research into the therapeutic usefulness of bacteriophages.The purpose of this review is to consider the prospects for the use of bacteriophages for the correction of the gut microbiota and therapy of digestive system diseases.The review describes the basics of phage biology, peculiarities of bacteriophage virome of the intestine in gastroenterological pathology; it highlights modern methods of phage-based therapy and prevention, considers problems of phage therapy and ways to overcome them. It is shown that the use of phages can become a key personalized approach to the treatment and prevention of infectious and non-infectious gastroenterological diseases.

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Section: современный потенциал терапии и профилактики на основе фаговunclassified

Personalized therapy with bacteriophages of digestive diseases

Гончар

Ермоленко²,

Скрипченко

2022

jour

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“…Кроме этого, наблюдается неадекватное назначение антибактериальных препаратов, включая неправильный выбор препарата, его дозы или определение продолжительности курса лечения, особенно в тех случаях, когда антибиотики назначаются эмпирически при лечении острой бактериальной патологии. В 2017 году Всемирная организация здравоохранения (ВОЗ) впервые опубликовала список устойчивых к действию антибиоти- [4,8,16].…”

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A Forgotten Group of Antibacterial Drugs

A.Ch.¹,

G.G.²

2021

Mil Med

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In recent years, considerable attention has been paid to the spread of bacterial resistance to antibiotics, disinfectants, and antiseptics. There are few effective antimicrobial drugs left, the creation of new ones requires significant costs. The WHO defines bacteriophages as a "new therapeutic approach" as an alternative in the fight against bacterial pathogens. Undoubtedly, healthcare organizers, epidemiologists and clinicians currently need an up-to-date assessment of the evidence regarding the benefits, efficacy and safety of bacteriophage therapy, as well as the use of phages for the control and prevention of infections (for example, in a complex of anti-epidemic measures, biological disinfection).

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Efficiency of phage therapy: methodological features of a systematic review

Cited by 2 publications

References 0 publications

Personalized therapy with bacteriophages of digestive diseases

Personalized therapy with bacteriophages of digestive diseases

A Forgotten Group of Antibacterial Drugs

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