Efficient Green Chemistry Approach for the Synthesis of 1,2,3-Triazoles Using Click Chemistry through Cycloaddition Reaction: Synthesis and Cytotoxic Study

Dexterous green synthesis of Cu2O nanoparticles: An amenable catalyst for aqueous click reaction, antiproliferative, and wound healing applications

“…A Thermo Scientific Nicolet iZ10 Module was used to record the infrared spectra in the range 4,000-500 cm À1 . Using a Bruker Advanced FT-NMR spectrometer, 1 H NMR (400 MHz) and 13 C NMR (100 MHz) spectra have been acquired utilizing CDCl 3 as the solvent with tetramethylsilane (TMS) as an internal standard. The J values are expressed in Hz, while the change in chemical shift values were put forth on a δ scale downfield from the TMS.…”

“…In the same vein, green chemistry along with click chemistry walk hand in hand down a road of meticulous regulations that assist to protect the wellbeing of the environment from imprudent and unrestrained production. 1 The ecologically amiable approach for forming carbon-heteroatom bonds, stated as "click chemistry" by Sharpless, has come to be known as one of the most adaptable and versatile way for coupling of two reactive partners. 2 Although there are several other reactions that can produce 1,2,3-triazoles, Huisgen's 1,3-dipolar cycloaddition of azides and alkynes has emerged as the front-runner.…”

Regioselective Pd-Catalyzed Suzuki–Miyaura Borylation Reaction for the Dimerization Product of 6-Bromoimidazo[1,2-a]pyridine-2-carboxylate: Mechanistic Pathway, Cytotoxic and Tubercular Studies

“…Hybridization and dimerization concepts were introduced to avail the benefit of two or more heterocycles in a single molecular framework. Because of the previous rationale, and in continuation of ongoing research to find diverse structural leads with potential chemotherapeutic and antitubercular activities, 52 53 54 55 56 in the present study, a new series of hybrids ([6,6′-biimidazo[1,2- a ]pyridine]-2,2′-dicarboxamide, 7a – j ) were obtained from ethyl 6-bromoimidazo[1,2- a ]pyridine-2-carboxylate through self-dimerization by Suzuki–Miyaura cross-coupling reaction in a four-step procedure. These compounds were further screened for their in vitro anticancer activity against a panel of 60 human cancer cell lines (nine cancer panels) and H 37 Rv anti-tubercular screening.…”

HAuCl4 Catalyzed and Dibenzyl amine Centered A3 coupling reaction: Synthesis, Spectroscopic Proofing and Anti‐microbial Efficacy

“…[22] This study focuses on the synthesis of A 3 adducts of amines, aldehydes, and alkynes in relation to the described issues and as a continuation of our research in the green chemistry domain. [23][24][25][26] By including DBA as one of the colliding species, the Au salt acts as a catalyst to speed up the synthesis process proposed. The primary benefit of the recycled gold composite is that it may be used again and again without significant performance degradation.…”

“…Consequently, heterogeneous catalysts that may be recovered can play a role in the prevention or minimization of chemical wastes, especially in the context of large‐scale and industrial processes [22] . This study focuses on the synthesis of A 3 adducts of amines, aldehydes, and alkynes in relation to the described issues and as a continuation of our research in the green chemistry domain [23–26] . By including DBA as one of the colliding species, the Au salt acts as a catalyst to speed up the synthesis process proposed.…”