Efficient wound healing composite hydrogel using Egyptian Avena sativa L. polysaccharide containing β-glucan

Hosary, Rania El; El-Mancy, Shereen S.; Deeb, Kadriya S. El; Eid, Hanaa H.; Tantawy, Mona E. El; Shams, Manal M.; Samir, Rasha; Assar, Nouran Hamed; Sleem, Amany A.

doi:10.1016/j.ijbiomac.2019.11.046

Cited by 37 publications

(6 citation statements)

References 33 publications

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“…Oat fruits are typical also for the presence of proteins (glutelin, avenin), lipids (α- and β-avenotionin), steroid saponins, flavonoids (tricin, apigenin, luteolin-7-glucoside), and β-glucan [ 54 ]. Recently, several studies proved the anti-inflammatory effect and antibacterial activity of oat fruits on Gram-positive bacteria (including S. aureus ) [ 55 , 56 ].…”

Section: Medicinal Plants and Their Constituents With Antibacterial Activity Intended In The Treatment Of Skin Disorders According To Eurmentioning

confidence: 99%

Antibacterial Activity of Medicinal Plants and Their Constituents in the Context of Skin and Wound Infections, Considering European Legislation and Folk Medicine—A Review

Fialová

Rendeková

Mučaji

et al. 2021

IJMS

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Bacterial infections of skin and wounds may seriously decrease the quality of life and even cause death in some patients. One of the largest concerns in their treatment is the growing antimicrobial resistance of bacterial infectious agents and the spread of resistant strains not only in the hospitals but also in the community. This trend encourages researchers to seek for new effective and safe therapeutical agents. The pharmaceutical industry, focusing mainly on libraries of synthetic compounds as a drug discovery source, is often failing in the battle with bacteria. In contrast, many of the natural compounds, and/or the whole and complex plants extracts, are effective in this field, inactivating the resistant bacterial strains or decreasing their virulence. Natural products act comprehensively; many of them have not only antibacterial, but also anti-inflammatory effects and may support tissue regeneration and wound healing. The European legislative is in the field of natural products medicinal use formed by European Medicines Agency (EMA), based on the scientific work of its Committee on Herbal Medicinal Products (HMPC). HMPC establishes EU monographs covering the therapeutic uses and safe conditions for herbal substances and preparations, mostly based on folk medicine, but including data from scientific research. In this review, the medicinal plants and their active constituents recommended by EMA for skin disorders are discussed in terms of their antibacterial effect. The source of information about these plant products in the review is represented by research articles listed in scientific databases (Science Direct, PubMed, Scopus, Web of Science, etc.) published in recent years.

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Section: Medicinal Plants and Their Constituents With Antibacterial Activity Intended In The Treatment Of Skin Disorders According To Eurmentioning

confidence: 99%

Antibacterial Activity of Medicinal Plants and Their Constituents in the Context of Skin and Wound Infections, Considering European Legislation and Folk Medicine—A Review

Fialová

Rendeková

Mučaji

et al. 2021

IJMS

View full text Add to dashboard Cite

show abstract

“…Hosary et al [ 76 ] isolated glucan from the plant Avena sativa L. and demonstrated its anti-inflammatory capacity, showing its high potential for use as a wound-healing hydrogel; it also showed antimicrobial activity against Staphylococcus aureus and Micrococcus luteus .…”

Section: Polysaccharides From Agricultural Wastementioning

confidence: 99%

“…Rostami et al [ 79 ] extracted polysaccharides from Malva sylvestris and showed that Gram-positive bacteria ( Bacillus cereus PTCC 1015 and Staphylococcus aureus PTCC 1112) were less sensitive than Gram-negative bacteria ( Escherichia coli PTCC 1763 and S almonella typhimurium PTCC 1709) to the different polysaccharide extracts obtained. However, Hosary et al [ 76 ] developed a hydrogel using polysaccharides derived from Egyptian Avena sativa L. The developed product showed slight activity against Candida albicans and high activity only against the Gram-positive bacterial strains Staphylococcus aureus ATCC 297373 and Micrococcus luteus ATCC 10240, and none against the two Gram-negative strains used in the study, Escherichia coli ATCC 10536 and Pseudomonas aeruginosa ATCC 25619. In the same way, Hashemifesharaki et al [ 80 ] obtained polysaccharides by microwave-assisted extraction of marshmallow root and increased the antimicrobial activity of the polysaccharide extract mainly against Gram-positive bacteria, in particular, Staphylococcus aureus PTCC 1189 and Bacillus circulans ATCC 4516.…”

Section: Polysaccharides From Agricultural Wastementioning

confidence: 99%

Strategies to Increase the Biological and Biotechnological Value of Polysaccharides from Agricultural Waste for Application in Healthy Nutrition

Rivas

Casquete

Martı́n

et al. 2021

IJERPH

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Nowadays, there is a growing interest in the extraction and identification of new high added-value compounds from the agro-food industry that will valorize the great amount of by-products generated. Many of these bioactive compounds have shown beneficial effects for humans in terms of disease prevention, but they are also of great interest in the food industry due to their effect of extending the shelf life of foods by their well-known antioxidant and antimicrobial activity. For this reason, an additional research objective is to establish the best conditions for obtaining these compounds from complex by-product structures without altering their activity or even increasing it. This review highlights recent work on the identification and characterization of bioactive compounds from vegetable by-products, their functional activity, new methodologies for the extraction of bioactive compounds from vegetables, possibly increasing their biological activity, and the future of the global functional food and nutraceuticals market.

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“…Especially in plastic surgery, patients have obvious facial edema after the operation, which significantly affects their life and work. Effective incision management after the operation can not only reduce complications and human and material costs but also achieve rapid recovery and reduce unnecessary troubles to life and work caused by surgical complications (El Hosary et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Highly Water-Absorptive and Antibacterial Hydrogel Dressings for Rapid Postoperative Detumescence

Fang

Chen

et al. 2022

Front. Bioeng. Biotechnol.

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Postoperative wound edema, infection, and pain burden the patient’s life. Therefore, the purpose of this study is to develop an effective antibacterial, multifunctional application to prevent postoperative edema and relieve postoperative pain by making full use of the dehydrating and analgesic effects of magnesium sulfate (MgSO4), magnesium oxide (MgO), sodium alginate (SA), and sodium carboxymethyl cellulose (Na-CMC) to make a composite hydrogel, which can promote postoperative detumescence. MgSO4//MgO/SA/Na-CMC composite hydrogel dressings have outstanding mechanical properties, high water absorption, and good biocompatibility. MgO endows the hydrogel dressing with excellent antibacterial properties and better antibacterial activity against common bacteria and multidrug-resistant bacteria. In addition, MgSO4/MgO/SA/Na-CMC hydrogel dressing shows superior dehydration and analgesic properties in the postoperative nude mice model. This study shows that the multifunctional MgSO4/MgO/SA/Na-CMC composite hydrogel dressing developed as a surgical incision dressing has broad prospects in the prevention of incision infection, postoperative edema, and analgesia.

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Efficient wound healing composite hydrogel using Egyptian Avena sativa L. polysaccharide containing β-glucan

Cited by 37 publications

References 33 publications

Antibacterial Activity of Medicinal Plants and Their Constituents in the Context of Skin and Wound Infections, Considering European Legislation and Folk Medicine—A Review

Antibacterial Activity of Medicinal Plants and Their Constituents in the Context of Skin and Wound Infections, Considering European Legislation and Folk Medicine—A Review

Strategies to Increase the Biological and Biotechnological Value of Polysaccharides from Agricultural Waste for Application in Healthy Nutrition

Highly Water-Absorptive and Antibacterial Hydrogel Dressings for Rapid Postoperative Detumescence

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