Eficácia de bupivacaína e associação com dexmedetomidina em bloqueio do plano transverso abdominal guiado por ultrassom na dor após cirurgia abdominal

Aksu, Recep; Patmano, Gülçin; Biçer, Cihangir; Emek, Ertan; Çoruh, Aliye

doi:10.1016/j.bjan.2017.04.021

Cited by 11 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bupivacaine concentration was twice as our study, as well. Aksu et al ( 18 ) divided 93 patients who were submitted for lower abdominal surgery into three groups, and TAP block was performed after general anesthesia induction but before surgical incision. In the control group (C), for block, 20% mL saline 0.9% and in group B, 20 mL bupivacaine 0.5%, and in group BD, 20 mL bupivacaine 0.5% with 1.5 mcg/kg dexmedetomidine were used.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of Three Different Doses of Dexmedetomidine Added to Bupivacaine in Ultrasound-Guided Transversus Abdominis Plane Block; A Randomized Clinical Trial

et al. 2021

View full text Add to dashboard Cite

Background: Adding dexmedetomidine to bupivacaine has been shown to prolong the analgesic effects of the transversus abdominis plane (TAP) block. However, the optimal dose of this adjuvant drug is unclear. Objectives: Identifying optimal doses of dexmedetomidine added to bupivacaine in the TAP block. Methods: In this randomized controlled trial, 86 patients candidate for elective open inguinal herniorrhaphy under spinal anesthesia were divided randomly into three groups; low (L), medium (M), and high (H) dose of dexmedetomidine, that finally 80 cases ended the study and were analyzed. At the end of the surgery, the patients underwent ultrasound-guided TAP block. In all patients of the three groups, the analgesic base of the block was 20 mL bupivacaine 0.125% that was supplemented with 0.5, 1, or 1.5 µ/kg of dexmedetomidine in groups L, M, and H, respectively. Results: The maximum duration of the block was 4 hours in group L and 8 hours in groups M and H. None of the patients needed to receive analgesic at 0, 2, and 24 hours after the block. The dose of analgesic required in the first 8 hours of the block in groups M and H was less than in group L (P < 0.02). Patients in groups H and M were more satisfied with the block (P < 0.01) and experienced less pain compared with group L (P < 0.01). Drowsiness and sedation were observed in patients up to 4 hours after the TAP block, which was dependent on the dexmedetomidine dose (P < 0.01). Conclusions: Based on our results, the optimal dose of supplemental dexmedetomidine could be 1 µ/kg in the TAP block.

show abstract

Section: Discussionmentioning

confidence: 99%

“…In most studies performed so far, patients have been subjected to general anesthesia, and the TAP block performed after general anesthesia and before surgery ( 18 ). The drowsiness of patients after waking up have also been attributed to general anesthesia.…”

Section: Discussionmentioning

confidence: 99%