Eficácia do fipronil em cães infestados com diferentes cargas parasitárias de Ctenocephalides felis felis (Siphonaptera: Pulicidae)

Coelho, Cristiane Nunes; Batista, Lilian Cristina de Sousa Oliveira; Lambert, Monique Moraes; Nunes, Tiago Abrahão Pereira; Santos, Rosângela Rodrigues dos; Silva, None Diego Dias da; Correia, Thaís Ribeiro; Scott, Fábio Barbour

doi:10.1590/s0100-736x2015000300010

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Therefore, after spot-on use of the drug, according to the manual on the label, the drug's efficacy against fleas was 0.0% to 43.4% after one hour of infestation, and > 99% after 12 h of infestation (Halos et al, 2016). Local treatment of the dogs with 10% fipronil produced > 95% elimination of the ectoparasite fleas for 35 days after the animals had been infested with 100 or 300 non-fed fleas, and on the 42nd day, the efficiency decreased to 68% (Coelho et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of efficacy of a drug based on fipronil, ivermectin, and pyriproxyfen against ecto- and endoparasitic invasions of dogs and cats

Yuskiv,

Tishyn,

Yuskiv

2024

Regul. Mech. Biosyst.

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Ecto- and endoparasitic invasions of dogs and cats are treated using drugs based on fipronil, ivermectin, and pyriproxyfen. That is why our objective was performing a field study to measure the efficacy of a complex drug with different mechanisms of the actions of its active agents against ecto- and endoparastitic invasions of dogs and cats using the spot-on application method. The paper presents data of the efficiency of the complex drug PerFect TRIO, antiparasitic drops for spot-on use against ecto- and endoparasitic invasions of dogs and cats of different breeds, ages, sexes, and body mass. Parasitological study of dogs found parasitism by the fleas Ctenocephalides canis and Pulex irritans with the invasion intensity ranging 108 to 132 ectoparasite insects per animal, the average invasion intensity being 121.1 ± 3.17 ectoparasite insects per animal; Trichodectidae species such as Trichodectes canis, with the invasion intensity ranging 25 to 32 ectoparasite insects per 100 cm² of the body surface, averaging 28.6 ± 1.00 ectoparasite insects per 100 cm² of the body surface; and Trombidiformes such as Сheyletiella yasguri, the intensity being 24 to 41 ectoparasite mites per animal, the average intensity being 33.9 ± 2.52 mites per animal. According to the results of parasitological studies of cats, their bodies were parasitized by the fleas Ctenocephalides felis and Pulex irritans, with the invasion intensity ranging 58 to 80 ectoparasite insects per animal, with the average intensity of 67.7 ± 2.84 ectoparasite insects per animal, Trichodectidae species such as Felicola subrostratus with the invasion intensity of 17 to 26 ectoparasite insects per 100 cm² of the animal’s body surface, averaging 21.3 ± 1.38 ectoparasite insects per 100 cm² of the body surface; the ear mite Otodectes cynotis with the intensity ranging 4 to 9 mites per animal, the average intensity being 6.1 ± 0.7 mites per animal; and the endoparasite – the digestive-tract nematode Uncinaria stenocephala, with the invasion intensity (ІІ) of 28 to 41 eggs in one gram of feces (ЕGF), averaging 34.3 ± 2.06 ЕGF. In our study, local spot-on application of the tested drug PerFect TRIO, antiparasitic drops for dogs and cats, produced notable effects on wingless ectoparasite insects and acarians of the dogs. Therefore, the efficiency of the drug against Siphonaptera infestation of the dogs equaled 92.9% on the 8th h and 100% on the 24th and 72nd h; against Trichodectidae infestation, it was 91.5% effective on the first day and 100% on the second and seventh; against cheyletiellosis, it was 81.9% effective on the seventh day and 100% on days 14 and 21. As with the cats, parasitological studies found that the efficacy of the recommended doses of the tested drug against spontaneous Siphonaptera infestation was 92.0% on the 8th h and 100% on the 24th and 72nd h; against Felicola infestation, it was 90.6% effective on the first day and 100% on the second and seventh day; against otodectosis, the drug produced 81.4% efficacy on the 7th day and 100% on the 14th and 21st days; and against hookworm disease, the efficacy was 100% on days 7 and 14. Our field trials demonstrated that the tested antiparasitic drops for cats and dogs are easy-to-use, were well received by the animals regardless of breed, age, sex, body mass, and had no toxic impact on them, providing a broad range of treatment against ecto- and endoparasites of cats and dogs.

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Section: Discussionmentioning

confidence: 99%

Evaluation of efficacy of a drug based on fipronil, ivermectin, and pyriproxyfen against ecto- and endoparasitic invasions of dogs and cats

Yuskiv,

Tishyn,

Yuskiv

2024

Regul. Mech. Biosyst.

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The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

Rust

2017

Insects

114

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The cat flea Ctenocephalides felis felis (Bouché) is the most important ectoparasite of domestic cats and dogs worldwide. It has been two decades since the last comprehensive review concerning the biology and ecology of C. f. felis and its management. Since then there have been major advances in our understanding of the diseases associated with C. f. felis and their implications for humans and their pets. Two rickettsial diseases, flea-borne spotted fever and murine typhus, have been identified in domestic animal populations and cat fleas. Cat fleas are the primary vector of Bartonella henselae (cat scratch fever) with the spread of the bacteria when flea feces are scratched in to bites or wounds. Flea allergic dermatitis (FAD) common in dogs and cats has been successfully treated and tapeworm infestations prevented with a number of new products being used to control fleas. There has been a continuous development of new products with novel chemistries that have focused on increased convenience and the control of fleas and other arthropod ectoparasites. The possibility of feral animals serving as potential reservoirs for flea infestations has taken on additional importance because of the lack of effective environmental controls in recent years. Physiological insecticide resistance in C. f. felis continues to be of concern, especially because pyrethroid resistance now appears to be more widespread. In spite of their broad use since 1994, there is little evidence that resistance has developed to many of the on-animal or oral treatments such as fipronil, imidacloprid or lufenuron. Reports of the perceived lack of performance of some of the new on-animal therapies have been attributed to compliance issues and their misuse. Consequentially, there is a continuing need for consumer awareness of products registered for cats and dogs and their safety.

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Eficácia do fipronil em cães infestados com diferentes cargas parasitárias de Ctenocephalides felis felis (Siphonaptera: Pulicidae)

Cited by 2 publications

References 11 publications

Evaluation of efficacy of a drug based on fipronil, ivermectin, and pyriproxyfen against ecto- and endoparasitic invasions of dogs and cats

Evaluation of efficacy of a drug based on fipronil, ivermectin, and pyriproxyfen against ecto- and endoparasitic invasions of dogs and cats

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

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