El tratamiento con análogos de la LHRH en la pubertad avanzada de la niña no modifica la talla final. Estudio longitudinal frente a un grupo control

Present meta-analysis indicates that girls with EP spontaneously reach their MPH and that GnRH analog treatment does not widely change growth outcome. Differences among the selected studies for definition of EP, inclusion criteria, treatment duration, age at discontinuation of therapy, definition of AH may affect results. What is Known: • Early puberty represents a main cause of consultation in paediatric endocrinology offices due to concerns of both practitioners and parents. • Treatment with GnRH analogs is sometimes attempted with the aim to improve adult height. What is New: • Untreated and GnRH analog treated girls with early puberty reached similar adult height. • Adult height was consistent with mid-parental height in both untreated and GnRH analog treated girls with early puberty.

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Adult height after spontaneous pubertal growth or GnRH analog treatment in girls with early puberty: a meta-analysis

Bertelloni

Massart

Miccoli

et al. 2017

Eur J Pediatr

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Comments on 'Adult height after gonadotropin‐releasing hormone agonist treatment in girls with early puberty: A meta‐analysis'

Franzini

Yamamoto

Bolfi

et al. 2020

Clinical Endocrinology

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El tratamiento con análogos de la LHRH en la pubertad avanzada de la niña no modifica la talla final. Estudio longitudinal frente a un grupo control

Cited by 2 publications

References 28 publications

Adult height after spontaneous pubertal growth or GnRH analog treatment in girls with early puberty: a meta-analysis

Adult height after spontaneous pubertal growth or GnRH analog treatment in girls with early puberty: a meta-analysis

Comments on 'Adult height after gonadotropin‐releasing hormone agonist treatment in girls with early puberty: A meta‐analysis'

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