Elastography: history, principles, and technique comparison

Garra, Brian S.

doi:10.1007/s00261-014-0305-8

Cited by 146 publications

(125 citation statements)

References 35 publications

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“…21,59 Determining patient-specific material properties has been a subject of research effort in the last 20-30 years. 36 However, despite substantial progress, including recent advances in MR elastography, 11,93 in vivo quantification of soft tissue material properties still remains an unsolved challenge. Nevertheless it is now known that a lot can be achieved even without the knowledge of patient-specific properties of tissues.…”

Section: Discussionmentioning

confidence: 99%

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From Finite Element Meshes to Clouds of Points: A Review of Methods for Generation of Computational Biomechanics Models for Patient-Specific Applications

et al. 2015

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It has been envisaged that advances in computing and engineering technologies could extend surgeons' ability to plan and carry out surgical interventions more accurately and with less trauma. The progress in this area depends crucially on the ability to create robustly and rapidly patientspecific biomechanical models. We focus on methods for generation of patient-specific computational grids used for solving partial differential equations governing the mechanics of the body organs. We review state-of-the-art in this area and provide suggestions for future research. To provide a complete picture of the field of patient-specific model generation, we also discuss methods for identifying and assigning patient-specific material properties of tissues and boundary conditions.

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Section: Discussionmentioning

confidence: 99%

“…36,93 Steady progress has been made to quantify elastography in terms of the tissue stress parameters and viscoelastic properties. 11 As discussed by Bilston, 11 one of the key challenges is that MR elastography determines tissue properties only for small deformations within the linear range.…”

Section: Elastographymentioning

confidence: 99%

From Finite Element Meshes to Clouds of Points: A Review of Methods for Generation of Computational Biomechanics Models for Patient-Specific Applications

et al. 2015

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“…For few years, elastography has been used in adults to determine the tissue stiffness in tissues like the liver, kidney, lymph nodes, breast, prostate, pancreas and thyroid [17,18]. There are a number of scientific reports about the diagnostic value of elastography in the differentiation of thyroid nodules in adults; however, there are no studies on the applications of elastography in the diagnosis of thyroid gland in children [19,20,21,22].…”

Section: Discussionmentioning

confidence: 99%

Practical Application of Elastography in the Diagnosis of Thyroid Nodules in Children and Adolescents

et al. 2016

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Background: Ultrasound elastography is a noninvasive method of imaging based on the estimation of the mechanical properties of tissue. Data in adults indicate that decreased flexibility in comparison to the surrounding healthy tissue is characteristic of malignancy (in most thyroid carcinomas, except for follicular thyroid carcinoma). The purpose of our study was to assess the deformation of thyroid nodules and to evaluate the usefulness of elastography in predicting malignant thyroid nodules in adolescent patients. Methods: We examined 47 children with 62 thyroid nodules. All patients underwent elastography and fine needle aspiration cytology (FNAC). Results: Thirty-seven girls (79%) and 10 boys (21%) were included in the study. A strain ratio <2 was observed in 17 nodules (27% of the study group), a strain ratio between 2 and 4.9 in 34 nodules (55%) and a strain ratio >5 in 11 nodules (18%). According to cytological examination, 3 nodules (4.8% of the study group) were malignant. Two of them were hard (strain ratio ≥5), and 1 nodule had a strain ratio of 2. Conclusions: Our results suggest that elastography can be complementary to conventional ultrasonography and useful while making a decision about FNAC. At the same time, it should not replace the cytological assessment of thyroid nodules in children and adolescents.

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“…All procedures followed were in accordance with the ethical standards of the Ethical Commitee of the Tokushima University and with the Helsinki Declaration of 1975, as revised in 2008 (5). Informed consent was obtained from all patients for being included in the study.…”

Section: Methodsmentioning

confidence: 99%

Intraoral ultrasonography of tongue mass lesions

Sugawara¹,

Takahashi²,

Kawano³

et al. 2016

Dentomaxillofacial Radiology

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Objectives: To demonstrate the usefulness of intraoral ultrasonography (IOUS) for tongue mass lesions, we analyzed surgery cases excluding squamous-cell carcinoma and leukoplakia and compared IOUS and pathological findings. Methods: We used the hospital information system and Radiology Information System to evaluate the IOUS and pathological findings of patients who underwent surgeries for tongue masses in the past 11 years. Results: Surgeries for the tongues were performed in 268 cases. Imaging examinations were carried out in 52 (19.4%) cases including 42 (15.7%) cases by IOUS. The pathological results of the surgeries were as follows: 36 cases were inflammatory lesions, 74 cases were tumours, 131 cases were hyperplasia, 8 cases were cystic lesions and 19 cases were other miscellaneous lesions. On the other hand, the number of patients who received IOUS in the same period was 87, and 42 of them had surgeries. In 32 out of the 42 (76.2%) cases, pre-operative IOUS features matched with pathological results. Most of the haemangiomas and lipomas could be diagnosed by IOUS alone. Conclusions: IOUS of the tongue revealed the nature of the lesions including the border, size, location, depth, the presence or absence of a capsule and the internal structure including vascularity of the mass. The ultrasonographic findings well reflected the histological findings. IOUS is a simple and useful technique that provides additional information beyond inspection, clarifying the internal structure, blood flow and relationships with the adjacent tissues. In this article, we indicated 11 representative cases (fibrous polyp, haemangioma, pyogenic granuloma, lipoma, liposarcoma, chondroma, lymphangioma, schwannoma, neurofibroma, pleomorphic adenoma and amyloidosis) to show the usefulness of IOUS.

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Elastography: history, principles, and technique comparison

Cited by 146 publications

References 35 publications

From Finite Element Meshes to Clouds of Points: A Review of Methods for Generation of Computational Biomechanics Models for Patient-Specific Applications

From Finite Element Meshes to Clouds of Points: A Review of Methods for Generation of Computational Biomechanics Models for Patient-Specific Applications

Practical Application of Elastography in the Diagnosis of Thyroid Nodules in Children and Adolescents

Intraoral ultrasonography of tongue mass lesions

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