Elastography in prostate gland imaging and prostate cancer detection

Tyloch, Dominik; Tyloch, Janusz; Adamowicz, Jan; Juszczak, Kajetan; Ostrowski, Adam; Warsiński, Patryk; Wilamowski, J.; Ludwikowska, Joanna; Drewa, Tomasz

doi:10.11152/mu-1655

Cited by 21 publications

(12 citation statements)

References 68 publications

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“…What's more, strain elastography was more operator dependent and less reproducible in comparison with SWE. At present, SWE is broadly applied in various apparatus [10][11][12][13][14] with great feedback. However, there has been limited research in the usability of SWE in peripheral pulmonary lesions [15].…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: Application of Transthoracic Shear Wave Elastography in Evaluating Subpleural Pulmonary Lesions

Liu

Zhen

Zhang

et al. 2021

European Journal of Radiology Open

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Section: Introductionmentioning

confidence: 99%

RETRACTED: Application of Transthoracic Shear Wave Elastography in Evaluating Subpleural Pulmonary Lesions

Liu

Zhen

Zhang

et al. 2021

European Journal of Radiology Open

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“…Several studies have demonstrated the diagnostic performance of elastography for prostate cancer. In 2018, Tyloch et al reported a review of six meta-analyses that evaluated the use of elastography in the diagnosis of prostate cancer 17 . According to this study, the meta-analysis by Sang et al showed that the highest diagnostic performance, sensitivity, and speci city were 0.844 (range, 0.696-0.927) and 0.860 (range, 0.792-0.908) 2 .…”

Section: Discussionmentioning

confidence: 99%

Role of the elastography strain ratio using transrectal ultrasonography in the diagnosis of prostate cancer and clinically significant prostate cancer

Yoo

Koo

Chung

et al. 2022

Preprint

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INTRODUCTIONThis study investigated the efficacy of the elastography strain ratio (ESR) as a predictor of prostate cancer (PCa) in targeted prostate biopsy.METHODSIn total, 257 patients who underwent magnetic resonance imaging-targeted biopsy were enrolled. Before biopsy, we placed regions of interest (zone A and B) in the lesion and levator ani. The ESR was measured as zone A/zone B. Multivariate analyses were performed to predict PCa and clinically significant PCa.RESULTSThere were 206 (71.5%) positive cancer lesions. No difference in digit rectal examination findings was found between patients with and without PCa. For predicting clinically significant PCa, an ESR ≥ 6.8 was significantly higher in the PCa (+) group than in the PCa (−) group (p < 0.001). The area under the receiver operating characteristic curve (AUC) for the conventional variables (model 1) plus the ESR was 0.845, which was significantly higher than that for model 1 (p = 0.001). In prostate imaging reporting and data system score 3 lesions, an ESR ≥ 4.6 was a significant predictor of PCa (p = 0.002). The AUC in model 1 plus the ESR was 0.856, which was significantly higher than that in model 1 alone (p = 0.017).CONCLUSIONSThe ESR is useful for predicting clinically significant PCa.

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“…Numerous studies have shown that ultrasound (US) elastography can improve the accuracy of PCa diagnosis (24)(25)(26)(27)(28)(29), by evaluating the stiffness of the lesion (30) and guiding the targeted biopsy (29,31). To date, a prediction model that combines lesion elasticity with MP-MRI and clinical data in men with PSA grey zone levels has not been reported.…”

Section: Introductionmentioning

confidence: 99%

Development and validation of a nomogram for predicting prostate cancer in men with prostate-specific antigen grey zone based on retrospective analysis of clinical and multi-parameter magnetic resonance imaging/transrectal ultrasound fusion-derived data

Ding¹,

Wu²,

Song³

et al. 2020

Transl Androl Urol

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Background: Urologists face a dilemma when deciding whether prostate biopsy is required for patients with prostate-specific antigen (PSA) levels in the grey zone (4 to 10 ng/mL). Methods:We retrospectively analyzed data from consecutive patients with PSA levels in grey zone, who underwent targeted multiparametric magnetic resonance imaging (MP-MRI)/transrectal ultrasound (TRUS) fusion biopsy with elastography between November 2017 and December 2019 in our hospital. The patientse data including age, PSA, fPSA (free PSA), fPSA/PSA, PSA density (PSAD), prostate volume, elastography Q-analysis score (EQS), and prostate imaging-reporting and data system (PI-RADS) score were collected. The nomogram was built using logistic regression and the final cohort of patients was randomly divided into a training cohort (70%) and a validation cohort (30%) by R software. The models were evaluated by receiver operating characteristic curve (ROC) analysis and calibration curve analysis. The nomogram was constructed from the best model. Results: The final study cohort consisted of 155 patients (training cohort, 109 patients; validation cohort, 46 patients) with PSA in the grey zone, of which 36 patients were pathologically diagnosed with PCa. The EQS model, −EQS model, +EQS model were built. The +EQS model that consisted of fPSA/PSA, EQS, and PI-RADS score had the best PCa diagnostic accuracy (development and validation, 0.783 and 0.781) and probability score (development and validation, 0.939 vs. 0.622). The new nomogram based on this model was constructed, in which fPSA/PSA ratio had the largest impact, followed by PI-RADS and EQS.Conclusions: Elastography and pre-biopsy MP-MRI has clinical significance for patients with PSA in the grey zone. The new nomogram, which is based on pre biopsy data including serological analysis, PI-RADS score, and EQS, can be helpful for clinical decision-making to avoid unnecessary biopsy.

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Elastography in prostate gland imaging and prostate cancer detection

Cited by 21 publications

References 68 publications

RETRACTED: Application of Transthoracic Shear Wave Elastography in Evaluating Subpleural Pulmonary Lesions

RETRACTED: Application of Transthoracic Shear Wave Elastography in Evaluating Subpleural Pulmonary Lesions

Role of the elastography strain ratio using transrectal ultrasonography in the diagnosis of prostate cancer and clinically significant prostate cancer

Development and validation of a nomogram for predicting prostate cancer in men with prostate-specific antigen grey zone based on retrospective analysis of clinical and multi-parameter magnetic resonance imaging/transrectal ultrasound fusion-derived data

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