Elastometry and Clinical Results After Bipolar Radiofrequency Treatment of Skin

Willey, Andrea; Kilmer, Suzanne L.; Newman, James; Renton, Bradley; Hantash, Basil M.; Krishna, Suhas; McGill, Scott; Berubé, Dany

doi:10.1111/j.1524-4725.2010.01563.x

Cited by 28 publications

(39 citation statements)

References 16 publications

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“…These data are consistent with the literature, 13 and are in favor of the bipolar technology, as the elastic fibers seem to significantly decrease after monopolar treatment. 2 The epidermis did not display any significant damage apart from a transient erythema at the end of the in vivo treatments.…”

Section: Discussionsupporting

confidence: 92%

The Biological Effects of Quadripolar Radiofrequency Sequential Application: A Human Experimental Study

Nicoletti

Cornaglia

Faga

et al. 2014

Photomedicine and Laser Surgery

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Objective: An experimental study was conducted to assess the effectiveness and safety of an innovative quadripolar variable electrode configuration radiofrequency device with objective measurements in an ex vivo and in vivo human experimental model. Background data: Nonablative radiofrequency applications are wellestablished anti-ageing procedures for cosmetic skin tightening. Methods: The study was performed in two steps: ex vivo and in vivo assessments. In the ex vivo assessments the radiofrequency applications were performed on human full-thickness skin and subcutaneous tissue specimens harvested during surgery for body contouring. In the in vivo assessments the applications were performed on two volunteer patients scheduled for body contouring surgery at the end of the study. The assessment methods were: clinical examination and medical photography, temperature measurement with thermal imaging scan, and light microscopy histological examination. Results: The ex vivo assessments allowed for identification of the effective safety range for human application. The in vivo assessments allowed for demonstration of the biological effects of sequential radiofrequency applications. After a course of radiofrequency applications, the collagen fibers underwent an immediate heat-induced rearrangement and were partially denaturated and progressively metabolized by the macrophages. An overall thickening and spatial rearrangement was appreciated both in the collagen and elastic fibers, the latter displaying a juvenile reticular pattern. A late onset in the macrophage activation after sequential radiofrequency applications was appreciated. Conclusions: Our data confirm the effectiveness of sequential radiofrequency applications in obtaining attenuation of the skin wrinkles by an overall skin tightening.

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Section: Discussionsupporting

confidence: 92%

The Biological Effects of Quadripolar Radiofrequency Sequential Application: A Human Experimental Study

Nicoletti

Cornaglia

Faga

et al. 2014

Photomedicine and Laser Surgery

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“…The elastosis score was also statistically significantly lower after the treatments, which is in agreement with elastometry findings after using another fractional RF system equipped with 5-microneedle-electrode pairs. 40 A previous study demonstrated that 90% of subjects with skin type II to IV showed improvement in smoothness and wrinkling, 87% in skin tightness, and 83% in skin brightness 1 month after three sublative RF treatments. 38 On the other hand, Wanner and colleagues showed that 73% of patients had 51% to 75% improvement in facial photodamage 9 months after a series of nonablative FP resurfacing.…”

Section: Discussionmentioning

confidence: 98%

Fractional Rejuvenation Using a Novel Bipolar Radiofrequency System in Asian Skin

Lee¹,

Lee

Won

et al. 2011

Dermatologic Surgery

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“…Elastic fiber regeneration has been reported following radiofrequency treatments 21 with evidence of a juvenile reticular pattern. 22 Therefore, our results are likely to be related to the radiofrequency sequential applications.…”

Section: Discussionmentioning

confidence: 99%

Scar Remodeling with the Association of Monopolar Capacitive Radiofrequency, Electric Stimulation, and Negative Pressure

Nicoletti

Perugini

Bellino

et al. 2017

Photomedicine and Laser Surgery

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Objective: A study was established to objectively assess the effects of low-intensity electromagnetic and electric stimulation plus negative pressure on mature scars. Background: Radiofrequency plus negative pressure therapy demonstrated a favorable reorganization and regeneration of the collagen and elastic fibers and was proposed for the treatment of cellulitis and skin stretch marks. Methods: Twenty-six mature scars in 20 Caucasian patients (15 females and 5 males) were enrolled in the study. The treatments were carried out with a Class I, BF-type electromedical device equipped with a radiofrequency generator, an electric pulse generator, and a vacuum pump twice a week for 3 months. Corneometry, transepidermal water loss, elastometry, colorimetry, and three-dimensional skin surface pattern were objectively assessed with Multi Probe Adapter System MPA and PRIMOS pico. A subjective assessment was carried out with the VAS and PSAS scales. Each scar was compared before and after the treatment and with the skin in the corresponding healthy contralateral anatomical area at the same times. Results: Reduction of the scar surface wrinkling and overall scar flattening were demonstrated after the treatment. The scar slightly tended to approach the color and elasticity of healthy skin too. Conclusions: The combined local treatment of mature scars with low-intensity electromagnetic and electric stimulation in association with negative pressure might suggest a favorable synergic effect on the scar collagen and elastic fiber remodeling.

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Elastometry and Clinical Results After Bipolar Radiofrequency Treatment of Skin

Cited by 28 publications

References 16 publications

The Biological Effects of Quadripolar Radiofrequency Sequential Application: A Human Experimental Study

The Biological Effects of Quadripolar Radiofrequency Sequential Application: A Human Experimental Study

Fractional Rejuvenation Using a Novel Bipolar Radiofrequency System in Asian Skin

Scar Remodeling with the Association of Monopolar Capacitive Radiofrequency, Electric Stimulation, and Negative Pressure

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