Elective Cesarean Delivery at Term and the Long-Term Risk for Neurological Morbidity of the Offspring

Baumfeld, Yael; Wainstock, Tamar; Segal, Idit; Sergienko, Ruslan; Landau, Daniella; Walfisch, Asnat

doi:10.1055/s-0038-1637001

Cited by 11 publications

(1 citation statement)

References 34 publications

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“…Zhang et al [110] reported no correlation between the procedure of cesarean section and the risk of developing depression, affective and non-affective psychosis. On the other hand, Baumfeld et al conducted a prospective cohort study and demonstrated that cesarean section was an independent factor affecting neurological disorders in children along with birth weight, maternal age, Apgar score, gestational age and the sex of the neonate [83]. Recent data by Sadowska et al [84] demonstrated that delivery by cesarean section increased the risk of epilepsy over two-fold (OR 2.17) in the patients with cerebral palsy.…”

Section: Discussionmentioning

confidence: 99%

Pediatrics Consequences of Caesarean Section—A Systematic Review and Meta-Analysis

Słabuszewska-Jóźwiak

Szymański

Ciebiera

et al. 2020

IJERPH

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Background: Cesarean section is a surgical procedure, which is the most frequently performed in gynecology and obstetrics. It is commonly believed that an operative delivery is a less painful and safer mode of delivery, which translates into an increasing number of the procedures performed without medical indications. The maternal sequelae of cesarean sections are well elucidated and widely discussed in the literature, while long-term neonatal consequences still remain the issue of research and scientific dispute. The aim of the present paper was to perform a systematic review of current literature regarding pediatrics consequences of cesarean section. Methods: We reviewed available data from PubMed, Science Direct as well as Google Scholar bases concerning early and long-term neonatal sequelae of operative deliveries. The following key words were used: “cesarean section”, “caesarean section”, “neonatal outcomes”, “respiratory disorders”, “asthma”, “obesity”, “overweight”, and “neurological disorders”. A total of 1636 papers were retrieved out of which 27 were selected for the final systematic review whereas 16 articles provided data for meta-analysis. Statistical analyses were performed using RevMan 5.4. To determine the strength of association between the caesarean section and respiratory tract infections, asthma, diabetes type 1 as well as obesity the pooled odds ratios (OR) with the 95% confidence intervals (CI) were calculated. Results: Conducted meta-analyses revealed that caesarean section is a risk factor for respiratory tract infections (pooled OR = 1.30 95%CI 1.06–1.60, p = 0.001), asthma (pooled OR = 1.23 95%CI 1.14–1.33, p < 0.00001) as well as obesity (pooled OR = 1.35 95%CI 1.29–1.41, p < 0.00001) in offspring. Conclusions: The results of the studies included indicated that children delivered by cesarean section more commonly developed respiratory tract infections, obesity and the manifestations of asthma than children delivered vaginally. The risk of developing diabetes mellitus type 1 or neurological disorders in offspring after caesarean section is still under discussion.

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Section: Discussionmentioning

confidence: 99%

Pediatrics Consequences of Caesarean Section—A Systematic Review and Meta-Analysis

Słabuszewska-Jóźwiak

Szymański

Ciebiera

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

The association between pregnancies complicated with isolated polyhydramnios or oligohydramnios and offspring long-term gastrointestinal morbidity

Amitai

Wainstock

Walfisch

et al. 2019

Arch Gynecol Obstet

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Delivery mode and future infectious morbidity of the offspring: a sibling analysis

Essa

Walfisch

Sergienko

et al. 2020

Arch Gynecol Obstet

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Elective Cesarean Delivery at Term and the Long-Term Risk for Neurological Morbidity of the Offspring

Abstract: Term elective CD is an independent risk factor for neurological morbidity of the offspring.

Cited by 11 publications

References 34 publications

Pediatrics Consequences of Caesarean Section—A Systematic Review and Meta-Analysis

Pediatrics Consequences of Caesarean Section—A Systematic Review and Meta-Analysis

The association between pregnancies complicated with isolated polyhydramnios or oligohydramnios and offspring long-term gastrointestinal morbidity

Delivery mode and future infectious morbidity of the offspring: a sibling analysis

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