Electric stimulation and hyperbaric oxygen therapy in the treatment of nonunions

Karamitros, Andreas; Kalentzos, V.; Soucacos, P.N.

doi:10.1016/j.injury.2006.02.042

Cited by 29 publications

(9 citation statements)

References 56 publications

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“…Radiation therapy results in progressive obliterative endarteritis, which leads to ischemia and a pathological fracture of the bone with reduced healing ability (23). Muhonen et al (24) evaluated the angiogenic and osteogenic responses after radiation and HBO in a rabbit mandibular distraction model.…”

Section: Discussionmentioning

confidence: 99%

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Neves¹,

Abib²,

Neves³

et al. 2013

Clinics

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OBJECTIVES:The purpose is to study the effects of hyperbaric oxygen therapy and autologous platelet concentrates in healing the fibula bone of rabbits after induced fractures.METHODS:A total of 128 male New Zealand albino rabbits, between 6–8 months old, were subjected to a total osteotomy of the proximal portion of the right fibula. After surgery, the animals were divided into four groups (n = 32 each): control group, in which animals were subjected to osteotomy; autologous platelet concentrate group, in which animals were subjected to osteotomy and autologous platelet concentrate applied at the fracture site; hyperbaric oxygen group, in which animals were subjected to osteotomy and 9 consecutive daily hyperbaric oxygen therapy sessions; and autologous platelet concentrate and hyperbaric oxygen group, in which animals were subjected to osteotomy, autologous platelet concentrate applied at the fracture site, and 9 consecutive daily hyperbaric oxygen therapy sessions. Each group was divided into 4 subgroups according to a pre-determined euthanasia time points: 2, 4, 6, and 8 weeks postoperative. After euthanasia at a specific time point, the fibula containing the osseous callus was prepared histologically and stained with hematoxylin and eosin or picrosirius red.RESULTS:Autologous platelet concentrates and hyperbaric oxygen therapy, applied together or separately, increased the rate of bone healing compared with the control group.CONCLUSION:Hyperbaric oxygen therapy and autologous platelet concentrate combined increased the rate of bone healing in this experimental model.

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Section: Discussionmentioning

confidence: 99%

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Neves¹,

Abib²,

Neves³

et al. 2013

Clinics

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show abstract

“…It is assumed that this potential has an important role in fracture healing. Numerous trials show the positive effect of electro stimulation on fracture healing, bone nonunions healing, and osseointegration of metal implants 10,11 . Isaacson and Bloebaum provided an excellent overview of the successful application of electricity.…”

Section: Introductionmentioning

confidence: 99%

Intraoperative measurement of bone electrical potential: a piece in the puzzle of understanding fracture healing

Žigman

Davila

Dobrić

et al. 2013

Injury

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“…Research is being undertaken worldwide in order to assess the influence of hyperbaric oxygen therapy on the formation of bone union. [5,6,7].…”

Section: Discussionmentioning

confidence: 99%

Patient Treatment Case Description in the Centre for Hyperbaric Oxygen and Wound Treatment in Bydgoszcz

Zieliński

Lipińska²,

Grobelska³

et al. 2015

Polish Hyperbaric Research

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Electric stimulation and hyperbaric oxygen therapy in the treatment of nonunions

Cited by 29 publications

References 56 publications

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Intraoperative measurement of bone electrical potential: a piece in the puzzle of understanding fracture healing

Patient Treatment Case Description in the Centre for Hyperbaric Oxygen and Wound Treatment in Bydgoszcz

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