Electrochemical biosensor for serogroup specific diagnosis of leptospirosis

Bothammal, Palanisamy; Michelraj, S.; Ganesh, V.; Verma, Ashutosh; Natarajaseenivasan, Kalimuthusamy

doi:10.1016/j.bioelechem.2021.108005

Cited by 3 publications

(2 citation statements)

References 38 publications

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“…The sensors detecting DNA or RNA of L. interrogans 41,44 are somewhat tedious to use as they require genetic material extraction and amplification steps. The antibody-detecting sensor 43 also requires some time for antibodies to develop, thus limiting its use during the initial stage of infection. Therefore, detection of leptospiral protein antigens would be very useful for early diagnosis of leptospirosis.…”

Section: Resultsmentioning

confidence: 99%

Electrochemical aptasensor detection of electron transfer flavoprotein subunit beta for leptospirosis diagnosis

Kositanont,

Srisawat,

Sripinitchai

et al. 2023

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Section: Resultsmentioning

confidence: 99%

Electrochemical aptasensor detection of electron transfer flavoprotein subunit beta for leptospirosis diagnosis

Kositanont,

Srisawat,

Sripinitchai

et al. 2023

Analyst

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“…Electrochemical biosensors for serogroup-specific diagnosis of leptospirosis are recently been reported from India, authors claim that it is a rapid, simple, and sensitive alternative to MAT [80 ▪ ].…”

Section: Challenges In the Laboratory Work Upmentioning

confidence: 99%

Ocular leptospirosis: lack of awareness among ophthalmologists and challenges in diagnosis

Sivakumar¹

2022

Current Opinion in Ophthalmology

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Purpose of reviewSystemic leptospirosis exists worldwide. But leptospiral uveitis, an important late complication is not identified by ophthalmologists in several countries.Recent findingsIn the last 18 months numerous publications, especially on epidemiology, surveillances, and novel rapid diagnostic kits to test at the point of care site on leptospirosis have been published from all over the world. However, publications from ophthalmologists are very scarce. Remarkably ophthalmologists should know the global burden of leptospirosis, prevalence of the disease in their country, demographic factors associated, risk factors, and systemic signs to elicit relevant history and travel history. They should be aware of recent advances in investigations to confirm their clinical diagnosis.SummaryIt is quite evident from this work that leptospirosis is prevalent worldwide. Ophthalmologists’ awareness has to improve to identify the etiological diagnosis. They should have access to simple, less expensive, and less cumbersome laboratory tests.

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Leptospiral lipopolysaccharide mediated Hog1 phosphorylation in Saccharomyces cerevisiae directs activation of autophagy

Bothammal

Prasad²,

Muralitharan³

et al. 2022

Microbial Pathogenesis

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Electrochemical biosensor for serogroup specific diagnosis of leptospirosis

Cited by 3 publications

References 38 publications

Electrochemical aptasensor detection of electron transfer flavoprotein subunit beta for leptospirosis diagnosis

Electrochemical aptasensor detection of electron transfer flavoprotein subunit beta for leptospirosis diagnosis

Ocular leptospirosis: lack of awareness among ophthalmologists and challenges in diagnosis

Leptospiral lipopolysaccharide mediated Hog1 phosphorylation in Saccharomyces cerevisiae directs activation of autophagy

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