Electrochemical biosensor for targeted detection in blood using aligned Au nanowires

Aravamudhan, Shyam; Ramgir, Niranjan S.; Bhansali, Shekhar

doi:10.1016/j.snb.2007.07.008

Cited by 90 publications

(38 citation statements)

References 26 publications

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“…Furthermore, I P increases with m 1/2 ( Fig. 4) and is directly proportional to concentration and the ratio of 3-/ 4-is one of the most extensively studied redox couples in electrochemistry, which exhibits a heterogeneous one electron transfer (n = 1).The calculated electroactive surface area of CCNT electrode was found to be 0.0765 cm 2 , where C = 10 -4 M, D = 6.5 9 10 -6 cm 2 /s for [Fe(CN) 6 ] 3-/4-system.…”

Section: Electrochemical Characterization Of Ccnt Electrodementioning

confidence: 92%

“…There is a strong positive correlation between high serum cholesterol level and arteriosclerosis, hypertension, and myocardial infarction. As biosensors have the ability to measure constantly the presence, absence, or concentration of specific organic or inorganic substances in desired test specimens, the thrust to monitor cholesterol in blood is driving the need for the development of efficient cholesterol biosensors to improve the life quality [2,3].…”

Section: Introductionmentioning

confidence: 99%

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Fabrication of a nonenzymatic cholesterol biosensor using carbon nanotubes from coconut oil

Saha

Das

2014

J Nanostruct Chem

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A nonenzymatic cholesterol biosensor was fabricated at the surface of carbon nanotube electrode (CCNT), obtained from coconut oil. The voltammetric behavior of cholesterol at CCNT electrode was investigated by cyclic voltammetry and differential pulse voltammetry in the presence of 0.001 M H 2 SO 4 as electrolyte . The influence of the experimental parameters on the peak currents of cholesterol like pH, accumulation time, and scan rates were optimized. Under optimum conditions, the peak current was found to be linear in the cholesterol concentration range from 1 to 50 lM with a sensitivity of *15.31 ± 0.01 lA lM -1 cm -2 and response time of about 6 s. Some characteristic studies of the nonenzymatic biosensor, such as reproducibility, substrate specificity, and storage stability have also been studied.

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Section: Electrochemical Characterization Of Ccnt Electrodementioning

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Fabrication of a nonenzymatic cholesterol biosensor using carbon nanotubes from coconut oil

Saha

Das

2014

J Nanostruct Chem

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“…Nanowires, with the characteristics of low weight with extraordinary mechanical, electrical, thermal, and multifunctional properties, have also been widely used in numerous bio-sensing applications (Curreli et al, 2005;Laocharoensuk et al, 2007;Roberts and Kelley, 2007;Shi et al, 2005;Wanekaya et al, 2006;Zhu et al, 2006). For example, some metal nanowires can be adopted in the detection of glucose (Cusma et al, 2007;Lu et al, 2007;Qu et al, 2007), cholesterol (Aravamudhan et al, 2007a;2007b), or DNA (Gao et al, 2007;Yi et al, 2010). Other types of nanowires have been exploited to detect inosine (Liu et al, 2006), bacterial (Basu et al, 2004;Garcia-Aljaro et al, 2010;Mishra et al, 2008), or cancer biomarkers (Choi et al, 2010;Ramgir et al, 2007;Zheng et al, 2005).…”

Section: Molecular Targets and Biomarker Sensingmentioning

confidence: 99%

Materiomics for Oral Disease Diagnostics and Personal Health Monitoring: Designer Biomaterials for the Next Generation Biomarkers

Zhang

Wang

Khalili

et al. 2016

OMICS: A Journal of Integrative Biology

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We live in exciting times for a new generation of biomarkers being enabled by advances in the design and use of biomaterials for medical and clinical applications, from nano-to macro-materials, and protein to tissue. Key challenges arise, however, due to both scientific complexity and compatibility of the interface of biology and engineered materials. The linking of mechanisms across scales by using a materials science approach to provide structure-process-property relations characterizes the emerging field of 'materiomics,' which offers enormous promise to provide the hitherto missing tools for biomaterial development for clinical diagnostics and the next generation biomarker applications towards personal health monitoring. Put in other words, the emerging field of materiomics represents an essentially systematic approach to the investigation of biological material systems, integrating natural functions and processes with traditional materials science perspectives. Here we outline how materiomics provides a game-changing technology platform for disruptive innovation in biomaterial science to enable the design of tailored and functional biomaterials-particularly, the design and screening of DNA aptamers for targeting biomarkers related to oral diseases and oral health monitoring. Rigorous and complementary computational modeling and experimental techniques will provide an efficient means to develop new clinical technologies in silico, greatly accelerating the translation of materiomics-driven oral health diagnostics from concept to practice in the clinic.

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“…(83) Furthermore, NMNWs have a large adsorption surface, high electrical conductivity and a smaller diffusion time, which endow a higher capture efficiency and a faster response time to analytes. (84) More importantly, networklike nanowires could …”

Section: Graphene-noble Metal or Graphene-transition Metal Nanohybridmentioning

confidence: 99%

A Review: Nanomaterials Applied in Graphene-Based Electrochemical Biosensors

2015

Sensors and Materials

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Owing to the outstanding conductivity and biocompatibility as well as numerous other fascinating properties of graphene, graphene-based nanohybrids have shown unparalleled superiorities in the field of electrochemical biosensors. We provide a general overview of recent advances and state-of-the-art works related to all types of nanomaterial, including noble metals, transition metals, organic and inorganic dyes, polymers, biomolecules, ionic liquids (ILs), and boronic acid derivatives, applied to functionalize graphene to construct electrochemical biosensors. We are highlighting here types of functionalization, assembly procedures, roles of nanomaterial, and assay strategies. Finally, some future perspectives and possible research directions are also discussed.

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Electrochemical biosensor for targeted detection in blood using aligned Au nanowires

Cited by 90 publications

References 26 publications

Fabrication of a nonenzymatic cholesterol biosensor using carbon nanotubes from coconut oil

Fabrication of a nonenzymatic cholesterol biosensor using carbon nanotubes from coconut oil

Materiomics for Oral Disease Diagnostics and Personal Health Monitoring: Designer Biomaterials for the Next Generation Biomarkers

A Review: Nanomaterials Applied in Graphene-Based Electrochemical Biosensors

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