Electrochemical biosensors based on nanomaterials for aflatoxins detection: A review (2015–2021)

Pérez-Fernández, Beatriz; Escosura‐Muñiz, Alfredo de la

doi:10.1016/j.aca.2022.339658

Cited by 55 publications

(23 citation statements)

References 100 publications

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“…Recently, different nanomaterials, such as carbon and metal, have been used to modify the active surfaces of macroelectrodes and microelectrodes to design electrochemical biosensors for the detection of AFB 1 [ 193 , 194 , 195 ]. This is because new biosensors directly use nanomaterials or other materials containing nanoparticles that show significant characteristics, such as high sensitivity and specificity for detecting targets, reliability, and consistency of products [ 181 , 196 , 197 ].…”

Section: Methods For Detecting Afb 1 In Edible Oilmentioning

confidence: 99%

Recent Progress on Techniques in the Detection of Aflatoxin B1 in Edible Oil: A Mini Review

2022

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Contamination of agricultural products and foods by aflatoxin B1 (AFB1) is becoming a serious global problem, and the presence of AFB1 in edible oil is frequent and has become inevitable, especially in underdeveloped countries and regions. As AFB1 results from a possible degradation of aflatoxins and the interaction of the resulting toxic compound with food components, it could cause chronic disease or severe cancers, increasing morbidity and mortality. Therefore, rapid and reliable detection methods are essential for checking AFB1 occurrence in foodstuffs to ensure food safety. Recently, new biosensor technologies have become a research hotspot due to their characteristics of speed and accuracy. This review describes various technologies such as chromatographic and spectroscopic techniques, ELISA techniques, and biosensing techniques, along with their advantages and weaknesses, for AFB1 control in edible oil and provides new insight into AFB1 detection for future work. Although compared with other technologies, biosensor technology involves the cross integration of multiple technologies, such as spectral technology and new nano materials, and has great potential, some challenges regarding their stability, cost, etc., need further studies.

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Section: Methods For Detecting Afb 1 In Edible Oilmentioning

confidence: 99%

Recent Progress on Techniques in the Detection of Aflatoxin B1 in Edible Oil: A Mini Review

2022

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“…Electrochemical methods are used to monitor isothermal amplification products using factors such as selectivity, sensitivity, speed, and cost [ 74 ]. The advantage of considering many factors makes electrochemical monitoring the most reliable and efficient method for analyte examination.…”

Section: Sensing Platform With Lampmentioning

confidence: 99%

Principles and Applications of Loop-Mediated Isothermal Amplification to Point-of-Care Tests

Park

2022

Biosensors

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For the identification of nucleic acids, which are important biomarkers of pathogen-mediated diseases and viruses, the gold standard for NA-based diagnostic applications is polymerase chain reaction (PCR). However, the requirements of PCR limit its application as a rapid point-of-care diagnostic technique. To address the challenges associated with regular PCR, many isothermal amplification methods have been developed to accurately detect NAs. Isothermal amplification methods enable NA amplification without changes in temperature with simple devices, as well as faster amplification times compared with regular PCR. Of the isothermal amplifications, loop-mediated isothermal amplification (LAMP) is the most studied because it amplifies NAs rapidly and specifically. This review describes the principles of LAMP, the methods used to monitor the process of LAMP, and examples of biosensors that detect the amplicons of LAMP. In addition, current trends in the application of LAMP to smartphones and self-diagnosis systems for point-of-care tests are also discussed.

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“…Reproducibility is the ability of biosensors to present the same result for a sample measured multiple times and reflects precision and accuracy. Enzyme‐based biosensors and immunosensors are susceptible to environmental interferences such as pH, stability, and other factors [81] . The aptasensor produces reproducible results with high reproducibility.…”

Section: Electrochemical Biosensors From Mxenes‐based Nanomaterialsmentioning

confidence: 99%

“…Enzyme-based biosensors and immunosensors are susceptible to environmental interferences such as pH, stability, and other factors. [81] The aptasensor produces reproducible results with high reproducibility.…”

Section: Aptamer-based Electrochemical Biosensors (Aptasensors)mentioning

confidence: 99%

Rapid Advances of Versatile MXenes for Electrochemical Enzyme‐Based Biosensors, Immunosensors, and Nucleic Acid‐Based Biosensors

Yao

Fan³

et al. 2022

ChemElectroChem

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Electrochemical biosensors have played an important role in clinical diagnostics, drug analysis, environmental monitoring, food safety, and other fields. Versatile two-dimensional (2D) MXenes-based nanomaterials, born with intrinsic peculiarities including high electrical conductivity, low toxicity, large specific surface area, and good biocompatibility, provide sufficient potential candidates for the construction of universal or specific electrochemical biosensors. In this review, we summarized the latest advances in 2D MXenes nanomaterials for constructing electrochemical enzyme-based biosensors, immunosensors, and nucleic acid-based biosensors in 2021, and then discussed the pertinent roles of corresponding 2D MXenes and carried out a comparison of the difference in the detection limit and detection range. Finally, challenges and future prospects of 2D MXenes-based electrochemical biosensors are proposed and discussed.

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Electrochemical biosensors based on nanomaterials for aflatoxins detection: A review (2015–2021)

Cited by 55 publications

References 100 publications

Recent Progress on Techniques in the Detection of Aflatoxin B1 in Edible Oil: A Mini Review

Recent Progress on Techniques in the Detection of Aflatoxin B1 in Edible Oil: A Mini Review

Principles and Applications of Loop-Mediated Isothermal Amplification to Point-of-Care Tests

Rapid Advances of Versatile MXenes for Electrochemical Enzyme‐Based Biosensors, Immunosensors, and Nucleic Acid‐Based Biosensors

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