Electrochemical study of β-Cyclodextrin binding with ferrocene tethered onto a gold surface via PAMAM dendrimers

Abstract

Este artigo descreve a fixação de ferrocenos (Fc) sobre eletrodos policristalinos de ouro, por filmes dendrímeros de poliamidoamina (PAMAM). A superfície eletroativa fornece uma rota viável para investigar quantitativamente a ligação do ferroceno com a ciclodextrina (CD). Em particular, as medidas eletroquímicas, revelam o efeito das interações adsorção-adsorção sobre a constante de associação K, na interface eletrodo-eletrólito, durante a formação do complexo de 1:1 Os resultados obtidos a partir da investigação da isoterma de adsorção de Frumkin indicam que as interações podem ter um forte impacto na afinidade do CD com as superfícies do ferrocenil modificado, estudadas aqui. A técnica apresentada pode ser útil para investigar outras reações de ligação entre hóspede-hospedeiro. This paper describes the tethering of ferrocene (Fc) onto polycrystalline gold electrodes by immobilized polyamidoamine (PAMAM) dendrimers films. The resulting electroactive surface provides a viable route for investigating quantitatively the host-guest binding of ferrocene with cyclodextrin (CD). In particular, electrochemical measurements reveal the effect of adsorbateadsorbate interactions on the association constant K for the formation of the 1:1 CD Fc complex at the electrode-electrolyte interface. The results obtained from fitting the Frumkin isotherm to the adsorption data indicate that adsorbate-adsorbate interactions can have a strong impact on the CD affinity for the ferrocenyl-modified surfaces studied here. The technique presented may be useful for investigating other host-guest binding reactions.

Controllable Molecule Transport and Release by a Restorable Surface-tethered DNA nanodevice

“…Compared with the device fabricated with Fc-DNA, the Fc signal of the device fabricated with β-CD-Fc-DNA cannot be detected either in “duplex state” or in “i-motif-triplex state”. This is also consistent with the fact that the signal of Fc has been blocked by the β-CD-Fc inclusion complex 46 47 . Therefore, it can be concluded that the “target molecule” β-CD can be loaded onto this DNA nanodevice accompanied with the hybridization of β-CD-Fc-DNA and Capture DNA-1.…”

Adhesive curing through low-voltage activation

“…This would allow further conduction of electrons via the intramolecular peptide branches. Sensors based on PAMAM dendrimers have been shown to be capable of electron transport 30 31 . Thus, electron hopping, tunneling or combinations thereof contributes to the observed bonding to the anode, cathode and bulk crosslinking.…”

Electrochemically driven host–guest interactions on patterned donor/acceptor self-assembled monolayers

“…Thus, as it is observed in Figure S5 and Figure S6 from ESI, the current intensity of the CV peaks decrease for both functionalized substrates after complexation. 52 Finally, in the XPS of the FcSH dil -SAM, the complex formation is proved by the appearance of new peaks at binding energies around 286 and 288 eV for the C1s and 533 eV for the O1s coming from the β-CD (Figure S7, ESI). In the AQSi-SAM, the news peaks around 286 and 533 eV confirms the presence of β-CD on the surface (Figure S8, ESI).…”