Electrochemical, Ultrasensitive, and Selective Detection of Nitrite and H₂O₂: Novel Macrostructured Phthalocyanine with Composite MWCNTs on a Modified GCE

Abstract

In the current study, the synthesis of tetra-4-(2-methoxyphenoxy) carboxamide cobalt(II) amide-bridged phthalocyanine (CoTMePhCAPc) is described, as well as its characterization by Fourier transform infrared (FT-IR), UV–visible, and mass spectroscopy; powder X-ray diffraction (PXRD); thermogravimetric analysis (TGA); scanning electron microscopy (SEM); and electrochemistry. Sensing of nitrite (NO2 –) and hydrogen peroxide (H2O2) simultaneously was done on CoTMePhCAPc with the composite multiwalled carbon nanotube (MWCNT)-modified glassy carbon electrode (CoTMePhCAPc/MWCNT/GCE) in the range of linear absorption (NO2 – and H2O2: CV 50–750, differential pulse voltammetry (DPV) 50–750, CA 50–500 nmol L–1), lower detection limit (NO2 – and H2O2: CV 10.5 and 12.5, DPV 10.5 and 11.2, CA 6.0 and 5.5 nmol L–1), and sensitivity (NO2 – and H2O2: CV 0.379 and 0.529, DPV 0.043 and 0.049, CA 0.033 and 0.040 μA nM–1 cm–2). The composite electrode exhibits improved electrocatalytic behavior compared to modified electrodes for nitrite and H2O2. The CoTMePhCAPc/MWCNT/GCE sensor displays good selectivity even in the presence of an excess of interfering metal ions and biomolecules at the applied potentials of +400 mV (nitrite) and −400 mV (H2O2). Moreover, the fabricated sensor was studied with various phosphate-buffered saline (PBS) (pH 5–9) electrolyte solutions. The unknown H2O2 concentration in blood samples and apple juice and nitrite concentration in drinking water and butter leaf lettuce were all measured using the usual addition method. Docking analysis clearly indicates that the ligand shows excellent inhibition activity toward the three subjected protein molecules.

Novel decorated aluminium(iii) phthalocyanine complex with the application of MWCNTs on electrodes: electrochemical non-enzymatic oxidation and reduction of glucose and hydrogen peroxide

“…However, more in-depth imaging further demonstrated the abundance of carbon nanotubes in the nanostructure of the crystallites. 39 4 Electrochemistry…”

CdO Decorated with Polypyrrole Nanotube Heterostructure: Potent Electrocatalyst for the Detection of Antihistamine Drug Promethazine Hydrochloride in Environmental Samples

“…From the abovementioned values, sensitivity (S) of the CdO@PPy/GCE was calculated and the numerical value is 0.13 μAμM –1 cm –2 . Limit of detection 10.83 nM was calculated using the following formula: LOD = 3σ / normalS where, S refers to the active surface area of the modified electrode and σ is the standard deviation of the blank. The formerly developed sensors toward PMH detection in comparison with the CdO@PPy/GCE are tabulated in Table .…”

An Electrochemical Sensor Based on Cu-MOF-199@MWCNTs Laden with CuNPs for the Sensitive Detection of Creatinine

“…Despite these merits, MOFs are often marred by poor stability in water and low conductivity . To overcome these challenges, MOFs are frequently amalgamated with stable electrocatalytic materials such as multiwalled carbon nanotubes (MWCNTs), renowned for their exceptional conductivity, mechanical stability, and robust adsorption properties . Such composites enhance MOFs’ conductivity and stability …”