Electrochemically synthesized partially reduced graphene oxide modified glassy carbon electrode for individual and simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid

Abstract

An electrochemically reduced graphene oxide modified glassy carbon electrode with good sensitivity and selectivity was developed and applied for sensing AA, DA and UA.

Simultaneous voltammetric detection of dopamine, ascorbic acid and uric acid using a poly(2-(N-morpholine)ethane sulfonic acid)/RGO modified electrode

“…For AA, the regression equations were i AA (10 mA) ¼ 0.49 + 0.038c AA (c AA : 1.0 mM-30 mM) (r ¼ 0.988) with a detection limit of 0.43 mM (S/N ¼ 3); i AA (10 mA) ¼ 1.3 + 0.01c AA (c AA : 30 mM-100 mM) (r ¼ 0.998). Compared with some reported methods, 15,37,39,40 this method had excellent analytical performances for detecting the AA, DA and UA (Table 1).…”

Simultaneous determination of dopamine, ascorbic acid and uric acid using a multi-walled carbon nanotube and reduced graphene oxide hybrid functionalized by PAMAM and Au nanoparticles

“…Abnormal concentration levels of UA indicate some diseases, such as gout, hyperuricemia and Lesch-Nyhan syndrome. 7,8 In the past half century, electrochemical techniques have led to a considerable amount of interest for the detection and quantication of AA, DA and UA, due to their rapid response, high sensitivity, low expense and simple operation. 9 Nevertheless, AA and UA normally exist together with DA in biological samples, and they are oxidized at nearby potentials.…”

Modified Electrodes for Selective Voltammetric Detection of Biomolecules

“…The electrochemically reduced graphene oxide has displayed the capacity to substantially improved the electron transfer kinetics of the electrode surface for electrooxidation of the biomolecules (Figure ) . The potential controlled partial reduction of graphene oxide is also helpful to improve the sensitivity and specifically selectivity for the certain biomolecules . Similarly, the L‐lysine was electropolymerized by successive direct electrochemical reduction of GO on the surface of GCE for simultaneous sensing of the analytes .…”