Electrochemiluminescence Sensing

Kotani, Akira

doi:10.2116/analsci.highlights2009

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…Electrochemiluminescence (ECL), also known as electrogenerated chemiluminescence, has been ramped out in diagnostic devices due to the properties of an electron transfer step at the electrochemical interface. 154 ECL involves the use of a co-reactant, which upon oxidation or reduction produces a moiety that on reaction with luminophore produces excitation. Oxidation or reduction takes place at the interface, and this generates reactive charged species that interact with luminophore to emit light.…”

Section: Point-of-care Diagnostics For Salivary Cortisolmentioning

confidence: 99%

Sensing methods for stress biomarker detection in human saliva: a new frontier for wearable electronics and biosensing

Pandit,

Crewther,

Cook

et al. 2024

Mater. Adv.

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Section: Point-of-care Diagnostics For Salivary Cortisolmentioning

confidence: 99%

Sensing methods for stress biomarker detection in human saliva: a new frontier for wearable electronics and biosensing

Pandit,

Crewther,

Cook

et al. 2024

Mater. Adv.

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“…These immunoassays are based on the optical emission from the excited states of a luminophore, usually, ruthenium complexes, produced by electrochemical reactions in the solution. 51,52 This method has many analytical applications, as it is highly sensitive and selective. However, the costs of automated equipment, which will carry out all the steps of a traditional immunoassay (immobilizations, reactions, and washes) standardized, and the generation of luminescence and analysis are considered a great challenge to overcome.…”

Section: Tablementioning

confidence: 99%

Evaluation of PAMAM Dendrimers (G3, G4, and G5) in the Construction of a SPR-based Immunosensor for Cardiac Troponin T

2021

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A SPR-based immunosensor was developed using a SAM of an alkanethiol associated with dendrimers PAMAM(G4) to enhance the sensitivity for troponin T detection in blood samples. The feasibility of using three-dimensional platforms based on dendrimers for the development of immunosensors was demonstrated by evaluating three different generations of these dendrimers (G3, G4, and G5) to detect troponin T.The results showed the efficiency of these 3D platforms in anchoring biomolecules, amplifying the detection of troponin T. The sandwich assay showed good performance for troponin T detection, using secondary monoclonal antibodies, in the concentration range of 5-300 ng mL −1 (0.14 -8.67 nmol L −1 ), R 2 =0.991, with a LOD of 3.6 ng mL −1 .The sandwich assay's applicability was demonstrated by evaluating a secondary polyclonal antibody's performance in the concentration range of 3-30 ng mL −1 , R 2 =0.998, with a LOD of 0.98 ng mL −1 . The immunosensor was applied to determine troponin T in blood plasma samples from healthy patients, with an average recovery of 88% to 104%. The performance of the SPR-based immunosensor indicates reliable results, contributing to the rapid diagnosis of heart attack, with reduced costs.

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Machine learning assisted and smartphone integrated homogeneous electrochemiluminescence biosensor platform for sample to answer detection of various human metabolites

Kumar,

Jain,

Bahuguna

et al. 2023

Biosensors and Bioelectronics

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Electrochemiluminescence Sensing

Cited by 3 publications

References 22 publications

Sensing methods for stress biomarker detection in human saliva: a new frontier for wearable electronics and biosensing

Sensing methods for stress biomarker detection in human saliva: a new frontier for wearable electronics and biosensing

Evaluation of PAMAM Dendrimers (G3, G4, and G5) in the Construction of a SPR-based Immunosensor for Cardiac Troponin T

Machine learning assisted and smartphone integrated homogeneous electrochemiluminescence biosensor platform for sample to answer detection of various human metabolites

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