“…(1). While examining both structural and functional brain abnormalities to demonstrate the etiology of this multifactorial disorder, some consistent findings have been reported to some extent, such as diffuse gray and white matter deficits and enlarged lateral ventricles (2)(3)(4). Periventricular leukomalacia (PVL) is a neurostructural change caused by periventricular white matter ischemia and since it mostly occurs in infants exposed to perinatal complications, studies are linking this early-acquired lesion with some neuropsychiatric diseases, including psychotic disorders (5).…”