Electromagnetic Field Effects on the Morphology of Rat Thyroid Gland

Matavulj, M.; Rajkovic, Vesna; Ušćebrka, Gordana; Žikić, Dragan; Stevanovic, D.; Lazetić, B

doi:10.1007/978-1-4615-4867-6_115

Cited by 5 publications

(5 citation statements)

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“…This is consistent with reports of the same finding in rats exposed to EMF (50·Hz, 50·T-500·T) from 24·h after birth for 2, 3 and 5·months (Matavulj et al, 1999;Rajkovic et al, 2001). This vascular effect of EMF might be exerted by the action of mediators from mast cells situated around blood vessels and/or nerve fibers terminating nearby, as indicated by our recent results.…”

Section: Table·1 the Number Of Observations Median Values With The supporting

confidence: 93%

“…Investigation on rats exposed to EMF (50·Hz, 50·T-500·T) for 7·h a day, 5·days a week, from the second postnatal day for 2·months yielded equivocal results of increased thyroid activity, as studied by a combination of classical histology and stereology (Matavulj et al, 1999). By contrast, in the thyroids of rats exposed to EMF for a longer period of 3, 5 and 6·months under the same experimental conditions there was morphological and stereological evidence for a decreased activity (Matavulj et al, 1999;Rajkovic et al, 2003). The degree of these changes correlated well with the duration of exposure.…”

Section: Discussionmentioning

confidence: 99%

“…Results of these studies demonstrated the effect of EMF on thyroid follicular epithelium, follicular colloid content, interfollicular connective tissue and mast cells (Matavulj et al, 1999;Matavulj et al, 2000;Rajkovic et al, 2003). The observed changes pointed to a decreased thyroid activity after 3, 5 and 6 months of exposure and enhanced thyroid activity after 2 months.…”

Section: Introductionmentioning

confidence: 93%

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Light and electron microscopic study of the thyroid gland in rats exposed to power-frequency electromagnetic fields

Rajkovic

Matavulj

Johansson

2006

Journal of Experimental Biology

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SUMMARY The effect of 50 Hz electromagnetic field (EMF) on thyroid gland was studied using light and transmission electron microscopes. Two-month-old male rats were exposed to an EMF (100-300 μT, 54-160 V m-1) for 4 h a day, 5 days a week for 1 month. A predominance of microfollicles with less colloid content and dilated blood capillaries was found in the EMF group. Stereological counting showed a statistically significant increase of the volume density of follicular epithelium, interfollicular tissue and blood capillaries as well as the thyroid activation index, as compared to the controls. The volume density of colloid significantly decreased. Ultrastructural analysis of thyroid follicular cells in the EMF group revealed the frequent finding of several colloid droplets within the same thyrocyte with the occasional presence of large-diameter droplets. Alterations in lysosomes, granular endoplasmic reticulum and cell nuclei compared to the control group were also observed. Taken together, the results of this study show the stimulative effect of power-frequency EMF on thyroid gland at both the light microscope and the ultrastructural level.

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Section: Table·1 the Number Of Observations Median Values With The supporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 93%

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Light and electron microscopic study of the thyroid gland in rats exposed to power-frequency electromagnetic fields

Rajkovic

Matavulj

Johansson

2006

Journal of Experimental Biology

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“…In line with our findings and based on light microscopic and ultrastructural data in rats, Rajkovic et al [] demonstrated stimulation of the thyroid gland by a power‐frequency electromagnetic field (EMF; 50 Hz, 100–300 μT, 54–160 V/m) immediately after exposure. The degree of structural changes in the thyroid correlated well with the duration of exposure, as activity decreased in rats exposed to the EMF for a longer period of time [Matavulj et al, ; Rajkovic et al, ]. In contrast to our results, changes in serum TSH and TH concentrations were not observed in rats exposed to a 50 Hz sinusoidal magnetic field of 0.75 mT for 3 h/day during 1 month [Sert et al, ] and humans acutely exposed to either continuous or intermittent 50 Hz linearly polarized magnetic fields of 10 μT [Selmaoui et al, ].…”

Section: Discussionsupporting

confidence: 47%

An Extremely Low Frequency Magnetic Field and Global Cerebral Ischemia Affect Pituitary ACTH and TSH Cells in Gerbils

Balind

Manojlović‐Stojanoski

Šošić‐Jurjević

et al. 2019

Bioelectromagnetics

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The neuroendocrine system can be modulated by a magnetic field and cerebral ischemia as external and internal stressors, respectively. This study deals with the separate or combined effects of an extremely low frequency (ELF) magnetic field (50 Hz, average magnetic field of 0.5 mT) for 7 days and global cerebral ischemia for 10 min on the morpho-functional features of pituitary adrenocorticotrophic (ACTH) and thyrotrophic (TSH) cells in 3-month-old gerbils. To determine the immediate and delayed effects of the applied stressors, measurements were made on the 7th and 14th days after the onset of the experiment. The ELF magnetic field and 10-min global cerebral ischemia, separately and particularly in combination, decreased (P < 0.05) the volume density of ACTH cells, while only in combination were intracellular ACTH content and plasma ACTH concentration increased (P < 0.05) on day 7. The ELF magnetic field elevated serum TSH concentration on day 7 and intracellular TSHβ content on day 14 (P < 0.05). Also, 10-min global cerebral ischemia alone increased serum TSH concentration (P < 0.05), while in combination with the ELF magnetic field it elevated (P < 0.05) intracellular TSHβ content on day 14. In conclusion, an ELF magnetic field and/or 10-min global cerebral ischemia can induce immediate and delayed stimulation of ACTH and TSH synthesis and secretion. Bioelectromagnetics. 2020;41:91-103.

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“…Furthermore, previous investigations of ELF–EMF effect on thyroid gland showed that rats exposed to ELF–EMF fields demonstrated altered thyroid gland activity [ 27 ]. Also, Matavulj et al [ 28 ] found that thyroid gland showed increased activity after 2 months of ELF-EMF exposure and decreased activity after 5 and 6 months, as measured by histological and stereological parameters. They concluded that the type of alteration depends on the duration of exposure and it is reflected as either increased or decreased activity of the thyroid.…”

Section: Discussionmentioning

confidence: 99%

Thyroid Hormone Indices in Computer Workers with Emphasis on the Role of Zinc Supplementation

Amin¹,

Hegazy²,

Ibrahim³

et al. 2016

Open Access Maced J Med Sci

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AIM:This study aimed to investigate the effects of computer monitor-emitted radiation on thyroid hormones and the possible protective role of zinc supplementation.MATERIAL AND METHODS:The study included three groups. The first group (group B) consisted of 42 computer workers. This group was given Zinc supplementation in the form of one tablet daily for eight weeks. The second group (group A) comprised the same 42 computer workers after zinc supplementation. A group of 63 subjects whose job does not entail computer use was recruited as a control Group (Group C). All participants filled a questionnaire including detailed medical and occupational histories. They were subjected to full clinical examination. Thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4) and zinc levels were measured in all participants.RESULTS:TSH, FT3, FT4 and zinc concentrations were decreased significantly in group B relative to group C. In group A, all tested parameters were improved when compared with group B. The obtained results revealed that radiation emitted from computers led to changes in TSH and thyroid hormones (FT3 and FT4) in the workers.CONCLUSION:Improvement after supplementation suggests that zinc can ameliorate hazards of such radiation on thyroid hormone indices.

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Electromagnetic Field Effects on the Morphology of Rat Thyroid Gland

Cited by 5 publications

References 9 publications

Light and electron microscopic study of the thyroid gland in rats exposed to power-frequency electromagnetic fields

Light and electron microscopic study of the thyroid gland in rats exposed to power-frequency electromagnetic fields

An Extremely Low Frequency Magnetic Field and Global Cerebral Ischemia Affect Pituitary ACTH and TSH Cells in Gerbils

Thyroid Hormone Indices in Computer Workers with Emphasis on the Role of Zinc Supplementation

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