“…Techniques used for the ESR study of caeruloplasmin and Fe transferrin in whole blood are identical to those previously described (Foster et al, 1977a …”
Summary.-Electron spin resonance studies have been made of caeruloplasmin and iron transferrin levels in whole blood of healthy controls and patients with a variety of malignant conditions receiving various forms of treatment.A small difference was found in caeruloplasmin level between normal males and females, although normal females receiving contraceptive steroids had an elevated level. No difference was found in iron transferrin level. Various conditions increased the caeruloplasmin and some also decreased the iron transferrin level in patients with malignant disease. These included surgery and the approach of a terminal phase of disease. Once allowance for these factors was made, the remaining small differences in Cu and Fe between patients with either squamous cell carcinoma or breast cancer and controls appeared to have no clinical significance.
“…Techniques used for the ESR study of caeruloplasmin and Fe transferrin in whole blood are identical to those previously described (Foster et al, 1977a …”
Summary.-Electron spin resonance studies have been made of caeruloplasmin and iron transferrin levels in whole blood of healthy controls and patients with a variety of malignant conditions receiving various forms of treatment.A small difference was found in caeruloplasmin level between normal males and females, although normal females receiving contraceptive steroids had an elevated level. No difference was found in iron transferrin level. Various conditions increased the caeruloplasmin and some also decreased the iron transferrin level in patients with malignant disease. These included surgery and the approach of a terminal phase of disease. Once allowance for these factors was made, the remaining small differences in Cu and Fe between patients with either squamous cell carcinoma or breast cancer and controls appeared to have no clinical significance.
“…plasma, and serum are iron transferrin with a signal This value was estimated from a receiver-operating of g Å 4.2 and the copper ceruloplasmin with a signal of g Å 2.049 (2,(4)(5)(6)(7)(8)(9)(10)(11)(12)14). In the pleural effusions, we also observed the signals with g Å 4.2 and 2.049.…”
Section: Origin Of Fe 3/ and Cu 2/ Signals From The Pleuralmentioning
confidence: 99%
“…Hodgkin's diseases showed higher ceruloplasmin inten-group (P õ 0.01). A fluctuation in the determination of the absolute signal intensity should be cancelled out sities and lower iron transferrin intensities than those with inactive disease (6). In our ESR measurements of by taking the ratio, which leads to the significant difference of the Cu 2/ /Fe 3/ ratios in the effusions.…”
Section: Origin Of Fe 3/ and Cu 2/ Signals From The Pleuralmentioning
confidence: 99%
“…nance (ESR) 1 method on blood (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Some authors The peak-to-peak height was used as a measure of sighave reported that the patients with the malignant nal intensity, since the signal was confirmed to have diseases such as cancer and Hodgkin's disease had a constant line width and line shape in all the samples.…”
“…Patients with clinically active Hodgkin's discasc show clevated caeruloplasmin e.s.r. signal sizc (Foster et a / , 1977b) which is currently used by these workers in routine managerncnt of patients. Slight elevations are also found in patients with non-Hodgkin's lymphoma (Foster et a / , 1977a) but it was felt that these findings were of less value in the clinical context.…”
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