Electrospinning and Electrospraying: Emerging Techniques for Probiotic Stabilization and Application

Feng, Kun; Huangfu, Lulu; Liu, C.-S.; Bonfili, Laura; Xiang, Qisen; Wu, Hong; Bai, Yanhong

doi:10.3390/polym15102402

Cited by 19 publications

(4 citation statements)

References 130 publications

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“…As mentioned earlier, the formation of beads by electrospraying and fibers via electrospinning depends on several factors, including the dispersion’s molecular weight, conductivity, surface tension, and viscosity. − Although PTFE provides good UV stability and chemical resistance, it exhibits relatively high electrical resistance and dielectric strength. These properties, along with the high surface tension and low viscosity of the PTFE dispersion, favor electrospraying of beads.…”

Section: Resultsmentioning

confidence: 99%

Synthesis, Optical Performance Characterization, and Durability of Electrospun PTFE–PEO Materials for Space Applications

Ibekwe,

Wang,

Bolzani

et al. 2024

ACS Appl. Mater. Interfaces

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Passive heat management is crucial in space, especially for extended missions involving protection from sunlight. Thermal coatings with desirable optical properties can drastically reduce the power consumed by active cooling systems, thereby reserving more resources for other critical systems onboard. Specifically, materials with wavelength-dependent reflectance and emittance are desirable for managing incident sunlight and self-cooling by thermal emission. This study demonstrates the use of polymer nanofibers, specifically poly(tetrafluoroethylene) (PTFE), for passive temperature control in space applications. This study describes the electrospinning fabrication process to create nanofibers and how process parameters can be varied to control the fiber geometry. We combine poly(tetrafluoroethylene) (PTFE) and poly(ethylene oxide) (PEO) polymers to fabricate highly reflective thermal control materials by electrospinning. To understand the role of material and fiber geometry, we measure spectral reflectance, absorptance, and transmittance using spectrophotometers interfaced with integrating spheres. We control the materials’ fiber geometry and solar reflectance by modifying the solution properties, flow rate, rotating collector speed, and fabrication time. With 220–1560 μm thick electrospun nanofiber materials, we demonstrate an average solar reflectance of 94.73–99.75%, with values approaching 99.9% for thicker samples, which is among the highest for space applications. Meanwhile, a thermal emittance of 81.4% was observed at 300 K for a 3360 μm thick sample. The durability of these samples was also tested under ultraviolet light and atomic oxygen. Compared to the state-of-the-art materials, the electrospun PTFE–PEO fibers present a new paradigm for passive thermal management in space applications.

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Section: Resultsmentioning

confidence: 99%

Synthesis, Optical Performance Characterization, and Durability of Electrospun PTFE–PEO Materials for Space Applications

Ibekwe,

Wang,

Bolzani

et al. 2024

ACS Appl. Mater. Interfaces

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“…Many of the limitations to bacterial cell viability described for electrospinning have a milder effect when using electrospraying because the mechanical (i.e., solvent evaporation and filament stretching) and electrical forces (employed electric field) are lower than those experienced in electrospinning. Nevertheless, achieving precise control over particle size and morphology remains a crucial goal, given their significant impact on the sustained release properties of bioactive compounds [ 64 ].…”

Section: Biofabrication Approachesmentioning

confidence: 99%

Emerging Multiscale Biofabrication Approaches for Bacteriotherapy

Rovelli,

Cecchini,

Zavagna

et al. 2024

Molecules

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Bacteriotherapy is emerging as a strategic and effective approach to treat infections by providing putatively harmless bacteria (i.e., probiotics) as antagonists to pathogens. Proper delivery of probiotics or their metabolites (i.e., post-biotics) can facilitate their availing of biomaterial encapsulation via innovative manufacturing technologies. This review paper aims to provide the most recent biomaterial-assisted strategies proposed to treat infections or dysbiosis using bacteriotherapy. We revised the encapsulation processes across multiscale biomaterial approaches, which could be ideal for targeting different tissues and suit diverse therapeutic opportunities. Hydrogels, and specifically polysaccharides, are the focus of this review, as they have been reported to better sustain the vitality of the live cells incorporated. Specifically, the approaches used for fabricating hydrogel-based devices with increasing dimensionality (D)—namely, 0D (i.e., particles), 1D (i.e., fibers), 2D (i.e., fiber meshes), and 3D (i.e., scaffolds)—endowed with probiotics, were detailed by describing their advantages and challenges, along with a future overlook in the field. Electrospinning, electrospray, and 3D bioprinting were investigated as new biofabrication methods for probiotic encapsulation within multidimensional matrices. Finally, examples of biomaterial-based systems for cell and possibly post-biotic release were reported.

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“…While probiotics have gained popularity for their potential health benefits, there are also some technical challenges associated with their use. Probiotics are vulnerable to adverse effects during processing, storage, and passage through the gastrointestinal tract, thus reducing their viability [ 137 ].…”

Section: Factors Determining the Stability Of Probioticsmentioning

confidence: 99%

Beneficial Bacteria Isolated from Food in Relation to the Next Generation of Probiotics

et al. 2023

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Recently, probiotics are increasingly being used for human health. So far, only lactic acid bacteria isolated from the human gastrointestinal tract were recommended for human use as probiotics. However, more authors suggest that probiotics can be also isolated from unconventional sources, such as fermented food products of animal and plant origin. Traditional fermented products are a rich source of microorganisms, some of which may have probiotic properties. A novel category of recently isolated microorganisms with great potential of health benefits are next-generation probiotics (NGPs). In this review, general information of some “beneficial microbes”, including NGPs and acetic acid bacteria, were presented as well as essential mechanisms and microbe host interactions. Many reports showed that NGP selected strains and probiotics from unconventional sources exhibit positive properties when it comes to human health (i.e., they have a positive effect on metabolic, human gastrointestinal, neurological, cardiovascular, and immune system diseases). Here we also briefly present the current regulatory framework and requirements that should be followed to introduce new microorganisms for human use. The term “probiotic” as used herein is not limited to conventional probiotics. Innovation will undoubtedly result in the isolation of potential probiotics from new sources with fascinating new health advantages and hitherto unforeseen functionalities.

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Electrospinning and Electrospraying: Emerging Techniques for Probiotic Stabilization and Application

Cited by 19 publications

References 130 publications

Synthesis, Optical Performance Characterization, and Durability of Electrospun PTFE–PEO Materials for Space Applications

Synthesis, Optical Performance Characterization, and Durability of Electrospun PTFE–PEO Materials for Space Applications

Emerging Multiscale Biofabrication Approaches for Bacteriotherapy

Beneficial Bacteria Isolated from Food in Relation to the Next Generation of Probiotics

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