Electrospun metal‐organic framework/polyacrylonitrile composite nanofibrous mat as a microsorbent for the extraction of tetracycline residue in human blood plasma

Abstract

A new composite nanofiber of polyacrylonitrile doped with copper benzene-1,3,5tricarboxylate metal-organic framework was fabricated by electrospinning and used as a microsorbent in the solid-phase extraction of trace tetracycline. The chemical structure of the adsorbent was studied by X-ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy, Brunauer-Emmett-Teller surface area analysis, and Barrett-Joyner-Halenda pore size and volume analysis techniques. The significant parameters of the method including desorption solvent kind and volume, adsorbent mass, pH, and salt percentage were investigated. At the optimized conditions, the linear range was 8-1000 μg/L with a determination coefficient (R 2 ) of 0.9954. The limits of detection and quantification were 2.40 and 8.00 μg/L, respectively. The inter-and intraday precisions were 4.7 and 3.4%, respectively. The developed extraction method was followed by high-performance liquid chromatography and applied for the determination of tetracycline in human blood plasma, and good relative recoveries (97.3-104.5%) were obtained. K E Y W O R D Santibiotics, electrospun composite nanofibers, high-performance liquid chromatography, metal-organic frameworks, polyacrylonitrile 1500

Integrated in‐syringe magnetic sheet solid‐phase extraction and dispersive liquid–liquid microextraction for determination of aflatoxins in fresh and moldy breads

“…The pH of the sample solution can influence the chemical stability of the target analytes and the surface charge of the adsorbent . Thus, it can have a significant impact on the effective interaction between 3D‐G‐Fe 3 O 4 and AFs.…”

Enhancing Solid-Phase Extraction of Tamoxifen and Its Metabolites from Human Plasma Using MOF-Integrated Polyacrylonitrile Composites: A Study on CuBTC and ZIF-8 Efficacy

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Monitoring of priority pollutants chlorophenols in water and milk by headspace solid‐phase microextraction based on electrospun polycaprolactam nanofibers decorated with cadmium oxide‐carbon nanotubes

“…The electrospun polymer nanofibers with remarkable properties such as large specific surface area, high porosity, and simple fabrication procedure have been used as an adsorbent in HS‐SPME. These materials are fabricated with the electrospinning technique by applying a high voltage electric field to an appropriate polymer solution [11,15,16].…”