Element−Element Addition to Alkynes Catalyzed by the Group 10 Metals

Enantioselective Platinum‐Catalyzed Silicon‐Boron Addition to 1,3‐Cyclohexadiene

“…Reaction of (S)-Mosher acid chloride with the product obtained using Pt(acac) 2 and (S)-9e as catalyst precursors yielded according to 1 H NMR spectroscopy a 6 : 1 mixture of two diastereomers, a ratio consistent with the 70% ee observed in the catalytic reaction. The signals from the olefinic protons as well as the methyl protons in the silyl substituent in the major Reactions performed in toluene at 110 8C.…”

Phosphoramidite: privilegierte Liganden in der asymmetrischen Katalyse

“…Übergangsmetallkatalysierte Additionen an Alkene gehören zu den wirksamsten Synthesemethoden, [403] und in den letzten Jahren wurden mehrere dieser Reaktionen erfolgreich mit einzähnigen Phosphoramidit-Liganden durchgeführt.…”

Palladium‐Catalyzed Annulation of vic‐Bis(pinacolatoboryl)alkenes and ‐phenanthrenes with 2,2′‐Dibromobiaryls: Facile Synthesis of Functionalized Phenanthrenes and Dibenzo[g,p]chrysenes

“…[5,6] Since the cross-coupling reaction of organoboron compounds (Suzuki-Miyaura coupling) is useful for stereospecific C sp 2 ÀC sp 2 bond formation and is compatible with a broad range of functional groups, [7] we focused our attention on vic-diborylalkenes [8] as potential precursors for our annulation approach. [9] Various vic-diborylated alkenes have been converted into multisubstituted acyclic alkenes by stepwise cross-coupling reactions with two organic halides, [10] whereas the double cross-coupling reaction of vic-diborylated compounds with aromatic dihalides as a synthetic method for functionalized PAHs remains unexplored. [11][12][13] We report herein a palladium-catalyzed double cross-coupling reaction of vic-diborylated alkenes (1) and phenanthrenes (2) Initially, we chose (Z)-1,2-bis(pinacolatoboryl)stilbene (1 a) as a model vic-diborylalkene and 2,2'-dibromobiphenyl (3 a) as a coupling partner [Eq.…”