Elemental compositions and anti-anemic property of Harungana madagascariensis stem bark

Abstract

The concentrations of 15 elements and heavy metals in the stem bark of Harungana madagascariensis were determined using an energy-dispersive Xray fluorescence (EDXRF) spectrometer. The anti-anemic activity was done using the changes in hematological parameters (PCV, RBC and Hb) influenced by phenylhydrazine HCL (80 mg/kg) and malaria parasitesinduced anemia. Results show Cd, Ni, Mo, Cr and Br were in the range of 0.02 -0.9 mg/g, while Pb, Zn, Fe, Cu and Hg were in the range of 1.5-7.2 mg/g. The elements with very high concentration were Ca, K, Sr, Mn and Cl and were in the range of 10.5-774.3 mg/g. Remarkable anti-anemic activity was obtained with PCV of 40-48%, RBC count of 81-155 x 10 4 and Hb value of 57-66 g/dL after treatment; compared with 30% PCV, 67 x 10 4 RBC count and 36.5 g/dL Hb value obtained for the untreated control animals. Our results suggest that H. madagascariensis stem bark extract constituents exhibit antianemic activity. Article Info

Medicinal plants and traditional healing practices in ehotile people, around the aby lagoon (eastern littoral of Côte d'Ivoire)

“…Pharmacological works have confirmed the important traditional use of this plant in the treatment of malaria. Indeed, the stem bark extract exhibited significant anti-protozoan effects against Trichomonas and Plasmodium both in vivo and in vitro [ 47 ] and also exhibit anti-anaemic activity, and it’s known that anaemia is a universal feature of malaria [ 48 ].…”

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