“…Introduced by Vining (37) in 1994, this was the first clinical application of vE, and it has since evolved to encompass virtual colon unfolding (36) and automated detection of polyps (39). Virtual bronchoscopy (10), virtual gastroscopy (6), and vE of the urinary tract (14) are other areas of application where evaluation of vE and translation into clinical practice are ongoing efforts. In otorhinolaryngology, vE has been used for endoscopic paranasal sinus surgery (1); in neurosurgery, vE has been used for simulation of ventriculoscopy (3,13,19,22) and cisternal endoscopy (2,12,17,26,31).…”