Elevated premature ventricular complex counts on 24-hour electrocardiogram predict incident atrial fibrillation and heart failure—A prospective population-based cohort study

Diagnostic reliability of monitoring for premature atrial and ventricular complexes

“… 32–34 Even modestly raised PAC frequencies 1 , 2 are associated with concurrent and incident atrial fibrillation, 35 while low levels of PVCs predict the risk of HF. 10 In the light of this, current consensus documents suggest imaging, electrical, and genetic evaluation in patients with ≥500 PVCs/24 h to exclude underlying disease, and screening for AF and sleep apnoea in patients with ≥500 PACs. 14 We observed such substantial day-to-day variability at PAC and PVC levels of 100–10 000/day that we would recommend 7-day recordings for patients with 100–10 000 beats on an initial 24 h ECG, in patients in whom the PAC or PVC frequency would influence a clinical decision to undertake further examinations.…”

Ventricular tachycardia risk prediction with an abbreviated duration mobile cardiac telemetry

“…In recent years, there has been an increasing research interest in the clinical significance of relatively low levels of PVCs, as they have been shown to predict future risk of heart failure and mortality. 16 , 17 However, PVCs, and by extension VTs, are a heterogeneous group of arrythmias with varying underlying mechanisms, and one could therefore argue that it is not enough to classify PVCs and VTs on quantity alone. 18 , 19 Other characteristics such as QRS duration, mono- or multiform complexes, morphology, and coupling interval to previous normal beat have been suggested as novel predictors of cardiovascular disease.…”