Élie Metchnikoff’s Legacy in the Field of Orthobiosis

Doskaliuk, Bohdana

doi:10.56543/aaeeu.2023.2.1.10

AAEE

2023

DOI: 10.56543/aaeeu.2023.2.1.10

|View full text |Cite

Élie Metchnikoff’s Legacy in the Field of Orthobiosis

Bohdana Doskaliuk

Abstract: Elie Metchnikoff is well known for his fundamental works in the field of cellular immunity and phagocytosis for which he was awarded the Nobel Prize. He gained his international reputation for ground-breaking research across numerous academic disciplines: biology, embryology, zoology, bacteriology, etc. The great visionary leader of science launched evolutionary embryology, comparative immunology, gerontology, to name a few. Most of his scientific works were influenced with philosophical reflections on the mea… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article3

Relationship

Self Cite1

Independent2

Authors

Journals

Cited by 3 publications

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

Luqman,

Hassan,

Ullah

et al. 2024

Front. Immunol.

View full text Add to dashboard Cite

The gut microbiome is a heterogeneous population of microbes comprising viruses, bacteria, fungi, and protozoa. Such a microbiome is essential for sustaining host equilibrium, and its impact on human health can be altered by a variety of factors such as external variables, social behavior, age, nutrition, and genetics. Gut microbes’ imbalances are related to a variety of chronic diseases including cancer, obesity, and digestive disorders. Globally, recent findings show that intestinal microbes have a significant role in the formation of cardiovascular disease (CVD), which is still the primary cause of fatalities. Atherosclerosis, hypertension, diabetes, inflammation, and some inherited variables are all cardiovascular risk variables. However, studies found correlations between metabolism, intestinal flora, and dietary intake. Variations in the diversity of gut microbes and changes in their activity are thought to influence CVD etiology. Furthermore, the gut microbiota acts as an endocrine organ, producing bioactive metabolites such as TMA (trimethylamine)/TMAO (trimethylamine N-oxide), SCFA (short-chain fatty acids), and bile acids, which have a substantial impact on host wellness and disease by multiple mechanisms. The purpose of this overview is to compile current evidence highlighting the intricate links between gut microbiota, metabolites, and the development of CVD. It focuses on how intestinal dysbiosis promotes CVD risk factors such as heart failure, hypertension, and atherosclerosis. This review explores the normal physiology of intestinal microbes and potential techniques for targeting gut bacteria for CVD treatment using various microbial metabolites. It also examines the significance of gut bacteria in disease treatment, including supplements, prebiotics, probiotics, antibiotic therapies, and fecal transplantation, which is an innovative approach to the management of CVD. As a result, gut bacteria and metabolic pathways become increasingly attractive as potential targets for CVD intervention.

show abstract

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

Luqman,

Hassan,

Ullah

et al. 2024

Front. Immunol.

View full text Add to dashboard Cite

show abstract

Aging and Geriatric Care: A Global Imperative Towards Universal Health Coverage

Singh,

Yadav,

Doskaliuk

2023

AAEE

Self Cite

View full text Add to dashboard Cite

The global population of older people is projected to surpass the number of children under 5 years old and adolescents by 2050, with developing countries housing the majority of older individuals. This demographic shift necessitates adjustments in global health systems to cater to the increasing demand for age-appropriate care. Gerontology, as an interdisciplinary field, encompasses the study of biological, social, and medical aspects of aging. Anti-aging, a distinct discipline, focuses on understanding and combatting age-related ailments. This review provides insights into the distinctive aspects of anti-aging research, highlights current priority issues in health promotion and anti-aging measures, and explores implications of crises on aging research and healthcare. Furthermore, it emphasizes the need for collaboration among interdisciplinary research networks, integration of science and technology, and the involvement of key stakeholders to ensure universal health coverage. Future research should address the multidimensional aspects of healthy aging, reflect research priorities and preferences of older individuals, and promote health equity. This collective effort will contribute to the development of innovative solutions and facilitate cross-learning among countries to enhance the well-being of aging populations globally.

show abstract

The Development of Geriatric and Anti-Aging Scientific School in Ukraine

Doskaliuk

2024

AAEE

View full text Add to dashboard Cite

This manuscript explores the historical development and significance of geriatric and anti-aging research in Ukraine, emphasizing its vital role in advancing global gerontology and geriatrics.The manuscript highlights the multidisciplinary aims of Ukrainian gerontological research, including understanding the biological mechanisms of aging, developing medical treatments for chronic diseases prevalent in older populations, and addressing the social and psychological aspects of aging. It also discusses the challenges of Ukraine’s aging population, such as healthcare policy reform, improved geriatric care integration, and increased funding for aging research. A significant emphasis is placed on incorporating anti-aging studies into medical education. By updating medical curricula to include comprehensive anti-aging education, Ukraine can better prepare future healthcare professionals to meet the evolving needs of its aging population. The manuscript concludes that such educational reforms are crucial for enhancing the effectiveness and sustainability of Ukraine’s healthcare system, ultimately improving the quality of life for older adults and aligning with global trends in aging research.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Élie Metchnikoff’s Legacy in the Field of Orthobiosis

Cited by 3 publications

References 8 publications

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

Aging and Geriatric Care: A Global Imperative Towards Universal Health Coverage

The Development of Geriatric and Anti-Aging Scientific School in Ukraine

Contact Info

Product

Resources

About