Aiming at the location research blank of the AG600 amphibious aircraft marine rescue base, the location decision index system of the AG600 is established, and the AG600 location decision model based on the interval intuitionistic fuzzy theory and improved TOPSIS method is constructed. Through investigation and statistical analysis, the evaluation system with 10 indices is determined based on applicability, safety, and accessibility, and in the process of quantization of index assignment, a fuzzy conversion method for different indices is proposed. The interval intuitionistic fuzzy number of each index is obtained by combining objective calculation and subjective assignment, and the interval intuitionistic fuzzy decision matrix is constructed. The fuzzy entropy method is used to calculate the index weight, and then the improved Technique for Order of Preference by Similarity (TOPSIS) is used to evaluate and rank the rescue bases. The scientific and reasonable location decision results are obtained. Finally, taking the South China Sea islands as an example, the correctness and reliability of the proposed model is verified by comparison with the calculation results of the score function method and the projection method.INDEX TERMS AG600 amphibious aircraft, interval intuitionistic fuzzy TOPSIS, location decision, marine rescue base.