Emerging infectious disease outbreaks: Old lessons and new challenges for obstetrician-gynecologists

Jamieson, Denise J.; Ellis, Jane; Jernigan, Daniel B.; Treadwell, Tracee A.

doi:10.1016/j.ajog.2005.06.062

Cited by 33 publications

(23 citation statements)

References 74 publications

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“…Experience from the international outbreak of severe acute respiratory syndrome (SARS) (33) can shed light on how to approach these complicated issues. In Toronto, obstetric services were moved into a newly designed facility that had entrances, elevators, and air-handling systems that were separate from the rest of the hospital.…”

Section: Pandemic Infl Uenza Response For Pregnant Women Nonpharmaceumentioning

confidence: 99%

Pandemic Influenza and Pregnant Women

Rasmussen

Jamieson

Bresee

2008

Emerg. Infect. Dis.

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307

248

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Planning for a future infl uenza pandemic should include considerations specifi c to pregnant women. First, pregnant women are at increased risk for infl uenza-associated illness and death. The effects on the fetus of maternal infl uenza infection, associated fever, and agents used for prophylaxis and treatment should be taken into account. Pregnant women might be reluctant to comply with public health recommendations during a pandemic because of concerns regarding effects of vaccines or medications on the fetus. Guidelines regarding nonpharmaceutical interventions (e.g., voluntary quarantine) also might present special challenges because of confl icting recommendations about routine prenatal care and delivery. Finally, healthcare facilities need to develop plans to minimize exposure of pregnant women to ill persons, while ensuring that women receive necessary care.

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Section: Pandemic Infl Uenza Response For Pregnant Women Nonpharmaceumentioning

confidence: 99%

Pandemic Influenza and Pregnant Women

Rasmussen

Jamieson

Bresee

2008

Emerg. Infect. Dis.

Self Cite

307

248

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“…Both clinical and experimental evidence demonstrates that the immune system during pregnancy is skewed to elicit predominantly Th2 responses, thus altering host susceptibility to various pathogens (121). Cytokines, such as interleukin-10 (IL-10), IL-5, and IL-4, predominate at the materno-fetal interface of the placenta, which is essential for maintenance of pregnancy (38,47).…”

Section: Neuroinflammatory Processesmentioning

confidence: 99%

Neuropathogenesis of Congenital Cytomegalovirus Infection: Disease Mechanisms and Prospects for Intervention

2009

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SUMMARY Congenital cytomegalovirus (CMV) infection is the leading infectious cause of mental retardation and hearing loss in the developed world. In recent years, there has been an improved understanding of the epidemiology, pathogenesis, and long-term disabilities associated with CMV infection. In this review, current concepts regarding the pathogenesis of neurological injury caused by CMV infections acquired by the developing fetus are summarized. The pathogenesis of CMV-induced disabilities is considered in the context of the epidemiology of CMV infection in pregnant women and newborn infants, and the clinical manifestations of brain injury are reviewed. The prospects for intervention, including antiviral therapies and vaccines, are summarized. Priorities for future research are suggested to improve the understanding of this common and disabling illness of infancy.

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“…L'émergence de nouvelles infections demandent tout particulièrement aux gynécologues-obstétriciens de s'informer régulièrement sur leurs risques potentiels maternofoetaux, mais aussi sur les traitements et leurs conséquences sur le développement de l'enfant. C'est important, non seulement pour apporter un diagnostic et un traitement rapides aux cas avérés d'infection, mais aussi pour informer les patientes sur les risques et leur prévention [18,24,25]. Il paraît tout aussi indispensable de poursuivre l'évaluation la plus complète possible des médicaments envisagés contre ces germes au cours de la grossesse et de leur passage transplacentaire afin de s'assurer de leur innocuité chez l'enfant [26].…”

Section: Resultsunclassified

Infections virales émergentes et grossesse

Ceccaldi

Longuet

Mandelbrot

2007

Gynécologie Obstétrique & Fertilité

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Various emerging diseases have been reported in recent years as epidemiologic monitoring improves. These infections can compromise the pregnancy, through adverse maternal outcomes, as well as the outcome for the child following transmission. We report a review of the literature concerning the most quoted emergent virus (H5N1, SARS Coronavirus, Chikungunya, West Nile virus), and relate the perinatal management.

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Emerging infectious disease outbreaks: Old lessons and new challenges for obstetrician-gynecologists

Abstract: All 3 outbreaks highlight the importance of obstetrician-gynecologists keeping current with new information as it emerges. In this global environment, it is likely that novel disease threats will continue to emerge in the United States.

Cited by 33 publications

References 74 publications

Pandemic Influenza and Pregnant Women

Pandemic Influenza and Pregnant Women

Neuropathogenesis of Congenital Cytomegalovirus Infection: Disease Mechanisms and Prospects for Intervention

Infections virales émergentes et grossesse

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