Emodin voltammetric sensor based on molecularly imprinted polymer membrane‐modified electrode using a multiple hydrogen bonds strategy

Abstract

Similar to those in complementary nucleotides' base pairs, we present a novel molecularly imprinted electrochemical sensor for emodin, constructed using a multiple hydrogen bonds strategy. We obtained the sensor by in situ photopolymerization, using allobarbital as a new functional monomer. We optimized the conditions of membrane imprinting and the composition of adsorption solvent. This artificial receptor exhibits high selectivity for the template in comparison with closely related analogs, aloin A and simetryne. The sensor was successfully applied in determination of emodin levels in one of the traditional Chinese medicines, the content of emodin in Sanhuang tablets detected using the voltammetric sensor and high performance liquid chromatography (HPLC) were 0.249 ± 0.009 (mg/tablet) and 0.246 ± 0.007 (mg/tablet), respectively. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012

Magnetic molecularly imprinted polymer for the selective extraction of quercetagetin from Calendula officinalis extract

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“…Up to now, a great deal of extraction or methods [1][2][3][4] have been developed to realize the extraction of natural products from TCM, but the low abundance, complex composition, thermosensitive and easily hydrolyze of the natural products increased the difficult for their extraction. At the same time, most of these methods are always high-cost and time-consuming in the preparation process [5], and majority of these methods could not obtain selective recognition during the extraction. Thus a material, which has high selectivity for target analytes and can be prepared without much labor was expected.…”

Bio-Mimetic Sensors Based on Molecularly Imprinted Membranes

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“…The novel sensor was tested for the determination of emodin content in Sanhuang tablets and compared with classical HPLC measurements. Results of these methods were about 2.49 × 10 −1 (mg·tablet −1 ) and 2.46 × 10 −1 (mg·tablet −1 ), respectively [ 296 ].…”

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