Emphysematous cystitis successfully treated with hyperbaric oxygen therapy: case report

Yasuhara, Hirotaka; Naito, Hiromichi; Kosaki, Yoshinori; Yamakawa, Yasuaki; Iida, Atsuyoshi; Yumoto, Tetsuya; Yamamoto, Hirotsugu; Yamada, Taihei; Tsukahara, Kohei; Osako, Takaaki; Mandai, Yasuhiro; Nakao, Atsunori

doi:10.22462/11.12.2018.13

Cited by 2 publications

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“…However, its typical manifestation is that of gas production during urination. 9 EC is typically intractable and persistent, with a long treatment time and a high recurrence rate. 10 It’s treatment can be made more difficult by a series of associated complications, leading to an entire urinary tract infection, renal dysfunction and the development of sepsis.…”

Section: Discussionmentioning

confidence: 99%

Severe emphysematous cystitis complicated with perforation, bilateral renal cortical atrophy and sepsis: a case report

2020

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Emphysematous cystitis (EC) is a rare bladder infection characterized by the presence of gas in the wall or cavity of the bladder. Most patients with EC will present with the typical symptoms of cystitis (e.g. frequent micturition, urgent micturition and dysuria), but other signs include distension and pain in the lower abdomen, drum sounds on percussion and a large amount of gas in the bladder. There can also be other complications such as sepsis. However, it is usually characterized by the typical symptoms of infection combined with pneumatinuria, the passage of gas mixed with urine. The early stage of EC is mostly limited to the submucosa and the symptoms of infection can be mild. Some patients may have no obvious clinical symptoms. If the infection becomes severe, it may result in difficulty urinating and kidney dysfunction. Therefore, timely treatment of these rare bladder infections is essential. This current case report describes an 80-year-old female patient with severe EC complicated by significant bilateral ureteral dilatation, bilateral renal cortical atrophy and sepsis. The patient was successfully treated with antibiotics and surgery. This report provides clinical data, test results and treatment experience that might be useful for clinicians that are involved in the treatment of EC.

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Section: Discussionmentioning

confidence: 99%

Severe emphysematous cystitis complicated with perforation, bilateral renal cortical atrophy and sepsis: a case report

2020

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“…Hyperbaric oxygen (HBO 2 ) is a UHMS-approved treatment for radiation cystitis [1]. In addition to radiation cystitis, the use HBO 2 has been reported in the treatment of other causes of cystitis including cyclophosphamide-induced hemorrhagic cystitis [2,3], BK virus-associated hemorrhagic cystitis [4,5], interstitial cystitis/painful bladder syndrome [6][7][8], emphysematous cystitis [9,10], and hemorrhagic cystitis following bone marrow transplantation [11]. The premise is that HBO 2 stimulates mucosal repair in the urinary bladder.…”

Section: Introductionmentioning

confidence: 99%

Two cases of Bacillus Calmette-Guérin cystitis treated with hyperbaric oxygen

Markovitz

2022

UHM

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Hyperbaric oxygen (HBO2) therapy is a UHMS-approved treatment for radiation cystitis and has been used for other causes of cystitis such as cyclophosphamide-induced hemorrhagic cystitis and interstitial cystitis, among others. Immunotherapy with Bacillus Calmette-Gu.rin (BCG) is the most effective treatment of non-muscle invasive bladder cancer. BCG acts as a non-specific stimulant of the reticuloendothelial system, causing a local inflammatory response. BCG attaches to bladder tumor cells as well as urothelial cells which then stimulates an immune response involving a multitude of cytokines and local migration of polymorphonuclear cells that leads to death of the cancer cells. The typical protocol of a single six-week course has been shown to provide long-term protection from tumor recurrence and to reduce disease progression. Irritative bladder side effects are common, but serious side effects are uncommon. Two cases of severe BCG-cystitis treated with HBO2 are presented. Two male patients with bladder cancer were treated with intravesicular BCG. Each developed complications of pain, spasms, urinary frequency and nocturia; one developed gross hematuria. Cystoscopy showed friable mucosa. They failed standard medical therapy and were referred for HBO2. They were treated in a multiplace chamber at 2.2-2.4 ATA. One patient received 60 and the other 40 treatments. Both experienced substantial reduction in their symptoms. BCG cystitis may be considered for HBO2 if other standard therapy has failed.

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Emphysematous cystitis successfully treated with hyperbaric oxygen therapy: case report

Cited by 2 publications

References 0 publications

Severe emphysematous cystitis complicated with perforation, bilateral renal cortical atrophy and sepsis: a case report

Severe emphysematous cystitis complicated with perforation, bilateral renal cortical atrophy and sepsis: a case report

Two cases of Bacillus Calmette-Guérin cystitis treated with hyperbaric oxygen

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