Enamel Erosion: A Possible Preventive Approach by Casein Phosphopeptide Amorphous Calcium Phosphate—An In Vitro Study

Abstract

A bstract Context Several efforts were made in order to alter the compositions of acidic food items concerning their properties to be able to reduce their erosivity potential. The addition of combinations of calcium and phosphate salts to these food products has grabbed great interest. Aim In vitro evaluation of the effect of the addition of 0.2% w/v casein phosphopeptide–amorphous calcium phosphate (CPP–ACP) to four commonly available beverages (of which two were carbonated) on enamel erosion. Materials and methods Sound-extracted human third molar teeth were taken, and enamel sections ( n = 270) were made and polished. Acid-resistant nail varnish was painted to create an exposed enamel window of 1 mm 2 , followed by testing of the four soft drinks and distilled deionized water (DDW). Every drink was evaluated with and without the addition of 0.2% w/v CPP–ACP. The enamel specimens were kept in 50 mL solution at 37°C for 30 minutes, rinsed, and then varnish was removed. All samples were then profiled using white-light profilometer, and erosive depths were recorded. Statistical analysis One-way analysis of variance test and post hoc Tukey test. Results Enamel erosion was created by all the soft drinks tested, but the addition of 0.2% w/v CPP–ACP has remarkably reduced ( p value < 0.05) erosive depths in all test solutions compared to solutions without CPP–ACP. The erosive depths for solutions with DDW did not vary much from those with 0.2% CPP–ACP. Conclusion Addition of 0.2% w/v CPP–ACP to the soft drinks has remarkably reduced their erosivity potential. How to cite this article Velagala D, Reddy VN, Achanta A, et al. Enamel Erosion: A Possible Preventive Approach by Casein Phosphopeptide Amorphous Calcium Phosphate—An In Vitro Study. Int J Clin Pediatr Dent 2020;13(5):486–492.

Potential of CPP-ACP and cranberry proantho-cyanidin chewing gum for remineralization of perimylolysis in eating disorders patients

“…However, the stability of CPP-ACP mineral deposits in exposed dentin can be affected by brushing, an acidic diet, and phosphatase production by oral bacteria. For this reason, continuous topical application is required to maintain significant precipitation formation of Ca2+ and PO43-ions on the tooth surface [14].…”

The Applications and Modifications of Casein Phosphopeptide-Amorphous Calcium Phosphate: An Update

“…6. Velagala et al [35] In-vitro study Decreased titratable acidity in all beverages with reduced loss of enamel. [52] These children have a high incidence of gastroesophageal reflux, thus a high risk of dental erosion.…”