Endarteritis and mycotic aortic aneurysm caused by an oral strain ofActinobacillus actinomycetemcomitans

Martín, M. Cruz; Andrés, María del Carmen Marca; Fierro, José F.; Méndez, Francisco Javier

doi:10.1007/bf01682165

Cited by 13 publications

(1 citation statement)

References 19 publications

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“…However, only a few authors have confirmed the simultaneous presence of A. actinomycetemcomitans in the periodontium and vascular walls [7,8]. Martin et al [53] reported the presence of the DNA of A. actinomycetemcomitans (the gene sequence encoding leukotoxin), originating from the oral cavity in an aortic aneurysm wall.…”

Section: Plos Onementioning

confidence: 99%

Periodontal status and the incidence of selected bacterial pathogens in periodontal pockets and vascular walls in patients with atherosclerosis and abdominal aortic aneurysms

et al. 2022

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The aim of the study was to examine the periodontal status of patients with atherosclerosis and abdominal aortic aneurysms. The occurrence of 5 periodontopathogens was evaluated in periodontal pockets and atheromatous plaques together with specimens from pathologically changed vascular walls of aortic aneurysms. The study comprised 39 patients who qualified for vascular surgeries. Patients with periodontitis and concomitant atherosclerosis or aneurysms were enrolled in the study. Periodontal indices were evaluated, and subgingival plaque samples were examined together with atheromatous plaques or specimens from vascular walls to identify, by polymerase chain reaction (PCR), the following periodontopathogens: Porphyromonas gingivalis, Tanarella forsythia, Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Treponema denticola. The majority of patients had chronic severe generalized periodontitis in stages III and IV. Laboratory investigations showed the occurrence of one or more of the five targeted periodontopathogens in 94.6% of the periodontal pockets examined. Of the examined periodontopathogens, only Porphyromonas gingivalis was confirmed in 1 atheromatous plaque sample collected from the wall of an aortic aneurysm. Therefore, the occurrence of this bacterium in these vessels was considered to be occasional in patients with chronic periodontitis.

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Section: Plos Onementioning

confidence: 99%