Endogenously expressed CXC chemokine receptor type 7 is involved in inflammation of chondrocyte from mice

Abstract

5W, 9W in each group in a random sample of3, application of chloral hydrate intraperitoneal injection anesthesia death, cardiac lavage after removing the damaged spinal cord tissue, immunohistochemical determination of GAP-43. Results: The first, to model after 1D,1W,2W,3W,5W,9W. BBB score, molding 1D after each score is 0points,1W groups of rat hindlimb has recovered, but the score is low, the group had no difference (P>0.05);2W B group, C group, D group was higher than that of A group were significantly different (P<0.05);3W,5W,9W score in group D was higher than that in group B, group C had significant difference (P<0.05). The second ,in the 1W,2W,3W,5W growth to protein GAP-43 immunohistochemical assay,1W group content were increased but no significant difference;2W,3W,5W B group, C group, D group was higher than that of A group were significantly different (P < 0.05), D group higher than that of B group, C group had significant difference (P < 0.01).The third in B group, C group, D group than in A group light complications. Conclusions: The BBB scoreandGAP-43detection, inference of electroacupuncture combined with OECs transplantation in treatment of spinal cord injury in rats at the axon growth there is a synergy, spinal nerve function is greatly improved.

Identification of SCRG1 as a Potential Therapeutic Target for Human Synovial Inflammation

“…For the six marker genes previously identified, we found that CDKN1A, FOSB, STMN2, and SLC2A3 genes were reported to be associated with cartilage inflammation in OA (40)(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(51). For example, the expression level of CDKN1A will increase correspondingly during cartilage degeneration (44), IL-17 and IL-1beta induced collagenase-3 production through AP-1 occurred with differential protein complex, and stimulation resulted in FOSB activation (52), STMN2 has significant differences between preserved and subchondral bone (48).…”