Endometriosis and Infertility

Ussia, Anastasia; Ph.R., Koninckx

doi:10.1001/jama.1956.02970230047014

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Cited by 7 publications

References 28 publications

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An Overview of Treatments for Endometriosis

Brown

Farquhar

2015

JAMA

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The levonorgestrel-releasing intrauterine system (LNG-IUD), gonadotropin-releasing hormone analogues (GnRHa; nafarelin, leuprolide, buserelin, goserelin, triptorelin), laparoscopic ablation, and excision are associated with relief of pain due to endometriosis. Gonadotropin-releasing hormone analogues and laparoscopic ablation or excision are associated with increased clinical pregnancy rates in women with endometriosis. Gonadotropin-releasing hormone analogues, danazol, and depot progestagens are associated with a higher incidence of adverse events.

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An Overview of Treatments for Endometriosis

Brown

Farquhar

2015

JAMA

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ART in Endometriosis

Kohls¹,

García-Velasco²

2018

Encyclopedia of Reproduction

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Evidence Linked Treatment for Endometriosis-Associated Infertility

Verma

2012

Apollo Medicine

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Endometriosis e defined as the presence of tissue similar to endometrium outside the uterine cavity, is commonly associated with infertility. The true prevalence remains obscure due to overall lack of well-designed epidemiologic studies. The disease has an enigmatic and multifaceted pathology which remains elusive despite decades of investigation. Despite all the uncertainties, it is established that treatment of endometriosis can improve fertility in some cases. Medical therapy although useful in reducing the severity of other symptoms of endometriosis such as pain and menstrual disorders, is not efficacious to improve fertility. Laparoscopic surgery apart from establishing the diagnosis, appears to be superior to expectant management or medical therapy. Controlled ovarian stimulation with intrauterine insemination is recommended in early stage and surgically corrected endometriosis when pelvic anatomy is normal. In advanced cases or moderate disease with associated tubal or male factors, in vitro fertilization is a treatment of choice. Despite all treatments, pregnancy rates remain lower in these women compared to diseasefree controls. Further well structured randomized clinical trials are necessary to reach any conclusive answers.

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Endometriosis and Infertility

Cited by 7 publications

References 28 publications

An Overview of Treatments for Endometriosis

An Overview of Treatments for Endometriosis

ART in Endometriosis

Evidence Linked Treatment for Endometriosis-Associated Infertility

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