Endoscopic and Bioptic Findings in the Upper Gastrointestinal Tract in Patients with Crohn's Disease

Alcántara, M; Rodríguez, Rosario; Potenciano, J. L. M.; Carrobles, J. L.; Muñoz, Cristina Lopez; Gómez, Rodolfo

doi:10.1055/s-2007-1010315

Cited by 104 publications

(45 citation statements)

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“…However, the positivity rate is low. 19,20 Few reports have examined the relationship between H. pylori infection of the stomach and gastric Crohn's disease, but the rate of H. pylori infection in patients with idiopathic inflammatory bowel disease (IBD) seems to be low, 21,22 and this appears to be related to treatment with SASP. 23 In our patient, tests for H. pylori were negative.…”

Section: Discussionmentioning

confidence: 99%

Pyloric stenosis due to Crohn's disease

Nakamura

Yanai

Miura³

et al. 1998

Journal of Gastroenterology

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Gastroduodenal involvement by Crohn's disease is relatively rare and occasionally causes pyloric stenosis, for which medical therapy may be ineffective and surgery may be required. We report on a 44-year-old man patient in whom corticosteroids had a marked effect in reducing pyloric stenosis caused by Crohn's disease. A proton-pump inhibitor was not effective, and Helicobacter pylori was negative.

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Section: Discussionmentioning

confidence: 99%

Pyloric stenosis due to Crohn's disease

Nakamura

Yanai

Miura³

et al. 1998

Journal of Gastroenterology

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“…8 In this context, radiology, serologic testing (ASCA; anti-Saccharaomyces cerevisiae and ANCA; anti-neutrophil cytoplasmic antibody), and upper endoscopy combined with random biopsies for evaluating granuloma are recommended. 9 Although endoscopic ultrasonography had been initially recognized to be effective in differentiating between CD and UC, it is now considered to have a limited function in this setting. 10 Novel diagnostic tools as wells as conventional endoscopy are needed to positively identify this group.…”

Section: Diagnosismentioning

confidence: 99%

Recent Advances of Endoscopy in Inflammatory Bowel Diseases

Cheon

Kim²

2007

Gut Liver

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“…Endoscopic and histologic involvement might be found in up to 40% of patients [84][85][86] . Due to the low frequency of patients with symptomatic gastroduodenal involvement, however, randomized, placebo-controlled trials are not available.…”

Section: Gastroduodenal CDmentioning

confidence: 99%

Conventional therapy for Crohn’s disease

Büning

Lochs²

2006

WJG

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Crohn's disease (CD) is a multifactorial disorder of unknown cause. Outstanding progress regarding the pathophysiology of CD has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD over the last years. However, many drugs have not been approved by regulatory authorities due to lack of efficacy or severe side effects. Therefore, well-known drugs, including 5-ASA, systemic or topical corticosteroids, and immunosuppressants such as azathioprine, are still the mainstay of CD therapy. Importantly, biologicals such as infliximab have shown to be efficacious in problematic settings such as fistulizing or steroid-dependent CD. This review is intended to give practical guidelines to clinicians for the conventional treatment of CD. We concentrated on the results of randomized, placebo-controlled trials and meta-analyses, when available, that provide the highest degree of evidence. We provide evidence-based treatment algorithms whenever possible. However, many clinical situations have not been answered by controlled clinical trials and it is important to fill these gaps through expert opinions. We hope that this review offers a useful tool for clinicians in the challenging treatment of CD.

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Endoscopic and Bioptic Findings in the Upper Gastrointestinal Tract in Patients with Crohn's Disease

Cited by 104 publications

References 0 publications

Pyloric stenosis due to Crohn's disease

Pyloric stenosis due to Crohn's disease

Recent Advances of Endoscopy in Inflammatory Bowel Diseases

Conventional therapy for Crohn’s disease

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